Seasonal variations in the survival index of rats at simulated high altitudes
Seasonal variations in the survival index of rats at simulated high altitudes
复制标题
DOI：
10.1007/bf01636121
复制
发表时间：
1966-01-01
影响因子：
3.2
通讯作者：
PURKAYASTHA, S. S.
中科院分区：
文献类型：
--
作者：
BHATIA, B.;THOMAS, S.;PURKAYASTHA, S. S.
白化大鼠饲养在动物舍内，其气温随环境温度的变化而波动。存活指数，定义为大鼠存活100分钟的百分比。在给定的模拟海拔高度下，对不同月份的几组大鼠进行了为期约1年的测定。所使用的模拟高度分别为25,000，27,500，30,000和32,500英尺，空气温度为33摄氏度，相对湿度超过80%，在减压室内。存活指数呈递减趋势，夏季平均气温从32℃下降到冬季的13℃，次年夏季气温升高。在从28摄氏度到1摄氏度的环境中移出的一组大鼠，存活指数在4周末显著下降，但在12周末没有显著下降。暴露在轻度寒冷中会降低大鼠在寒冷暴露10到30天之间耐缺氧的能力，这种能力往往会在30到90天之间恢复正常。|抽象作者：作者
Albino rats were maintained in an animal house, the air temperature of which fluctuated with the variations in the ambient air temperature. Survival index, which is defined as the percentage of rats surviving for 100 min. at a given simulated altitude, was determined for several groups of rats in different months covering a period of about 1 yr. The simulated altitudes used were 25,000, 27,500, 30,000 and 32,500 ft., with an air temperature of 33[degree] C and RH [relative humidity] of over 80%, within the decompression chamber. The survival index showed a progressive decline with the fall in mean air temperature of 32[degree] C in summer to 13[degree] C in winter, and a rise with increase in air temperature during the summer of the succeeding year. In a group of rats removed from an environment at 28[degree]C to 1 at 19[degree]Ca significant fall in survival index was observed at the end of 4 weeks, but not at the end of 12 weeks. Exposure to a mild degree of cold reduces the ability of rats to survive hypoxia between 10 and 30 days of cold exposure, which tends to revert to normal between 30 and 90 days. || ABSTRACT AUTHORS: Authors