Perception of prognostic risk in patients with multiple sclerosis:: the relationship with anxiety, depression, and disease-related distress
Perception of prognostic risk in patients with multiple sclerosis:: the relationship with anxiety, depression, and disease-related distress
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DOI：
10.1016/s0895-4356(03)00260-9
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发表时间：
2004-02-01
影响因子：
7.2
通讯作者：
Hintzen, RQ
中科院分区：
文献类型：
--
作者：
Janssens, ACJW;van Doorn, PA;Hintzen, RQ
目的：本研究的目的是探讨预后风险感知对多发性硬化症（MS）患者焦虑、抑郁和疾病相关痛苦的影响。研究设计和背景：对101例患者进行轮椅依赖、残疾状况、焦虑、抑郁和疾病相关困扰的2年、10年和终身预后的感知风险和感知严重性评估。痛苦是通过对ms相关想法和感受的侵入和回避来衡量的。结果：2年、10年或终生风险感知较高的患者更容易受到ms相关思想和感受的侵扰。只有较高的2年轮椅依赖风险感知与较高水平的焦虑、抑郁和回避显著相关。同样，对轮椅依赖严重程度的较高感知与更多的入侵和回避一致相关，但只有对轮椅依赖2年前景的感知严重性与焦虑和抑郁显著相关。所有关系与临床评估的残疾状况无关。结论：对轮椅依赖的短期风险和严重程度的认知与ms患者的焦虑、抑郁和疾病相关的痛苦显著相关。这些发现强调了告知慢性疾病患者疾病重要长期后果的短期预后的重要性。(C) 2004爱思唯尔公司版权所有。
Objective: The aim of the study was to investigate the impact of perception of prognostic risk on anxiety, depression, and disease-related distress in patients with multiple sclerosis (MS).Study Design and Setting: Perceived risk and perceived seriousness of the 2-year, 10-year, and lifetime prognosis of wheelchair dependence, disability status, anxiety, depression, and disease-related distress were assessed in 101 patients. Distress was measured as the intrusion and avoidance of MS-related thoughts and feelings.Results: Patients with higher perceptions of 2-year, 10-year, or lifetime risk were bothered by more intrusion of MS-related thoughts and feelings. Only higher perception of the 2-year risk of wheelchair dependence was significantly related with higher levels of anxiety, depression, and avoidance. Similarly, higher perception of the seriousness of wheelchair dependence was consistently associated with more intrusion and avoidance, but only perceived seriousness of the 2-year prospect of wheelchair dependence was significantly correlated with anxiety and depression. All relations were independent of clinically assessed disability status.Conclusion: Perceptions of the short-term risk and seriousness of wheelchair dependence were significantly related to anxiety, depression, and disease-related distress in patients with MS. These findings underscore the importance of informing patients with chronic disorders about the short-term prognosis of important long-term consequences of disease. (C) 2004 Elsevier Inc. All rights reserved.