FLUID BALANCE WITHIN CANINE ANTEROLATERAL COMPARTMENT AND ITS RELATIONSHIP TO COMPARTMENT SYNDROMES
FLUID BALANCE WITHIN CANINE ANTEROLATERAL COMPARTMENT AND ITS RELATIONSHIP TO COMPARTMENT SYNDROMES
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DOI：
10.2106/00004623-197860040-00012
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发表时间：
1978-01-01
影响因子：
5.3
通讯作者：
SCHMIDT, DA
中科院分区：
文献类型：
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作者：
HARGENS, AR;AKESON, WH;SCHMIDT, DA
肌肉腔室内的流体稳态由4种压力维持：毛细血管血压、毛细血管血液致瘤压力、组织液压力和组织液致瘤压力。犬前外侧腔室测得毛细血管血压为25 +-。3毫米汞柱;毛细血管肿瘤压，26 .+-。3毫米汞柱;组织流体压力-2 .+-。2毫米汞柱;组织液肿瘤压，11。1毫米汞柱。灯芯技术可以直接测量骨骼肌中的组织液压力，并且经过微小的修改，适用于收集组织间液的微样本以测定组织液的肿瘤压力。灯芯技术可以检测到室内压力的微小波动，如轻微的手指压迫、小体积液体的注射，甚至是由于邻近动脉压力引起的脉动。由于不透水的骨筋膜屏障，相邻的肌室可能含有不同的组织液压力。在犬的肌室中，通过输注自体血浆获得的结果表明，当室内压力大于30 mmHg时，肌肉损伤的风险显著。
Fluid homeostasis within muscle compartments is maintained by 4 pressures: capillary blood pressure, capillary blood oncotic pressure, tissue-fluid pressure and tissue-fluid oncotic pressure. As determined in the canine anterolateral compartment, capillary blood pressure is 25 .+-. 3 mmHg; capillary blood oncotic pressure, 26 .+-. 3 mmHg; tissue-fluid pressure, -2 .+-. 2 mmHg; and tissue-fluid oncotic pressure, 11 .+-. 1 mmHg. The wick technique allows direct measurement of tissue-fluid pressure in skeletal muscle and, with minor modifications, is adapted to collect microsamples of interstitial fluid for determinations of tissue-fluid oncotic pressure. The wick technique detects very slight fluctuations in intracompartmental pressure such as light finger compression, injection of small volumes of fluid and even pulsation due to adjacent arterial pressure. Adjacent muscle compartments may contain different tissue-fluid pressures due to impermeable osseofascial barriers. The results obtained in canine muscle compartments pressurized by infusion of autologous plasma suggest that risks of muscle damage are significant at intracompartmental pressures greater than 30 mmHg.