Metabolic targets in cardiac aging and rejuvenation
Metabolic targets in cardiac aging and rejuvenation
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DOI：
10.20517/jca.2022.31
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Chang Liu;Xiao Zhang;Meiyu Hu;Yi Lu;P. Gokulnath;Gururaja Vulugundam;Junjie Xiao
中科院分区：
文献类型：
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作者：
Chang Liu;Xiao Zhang;Meiyu Hu;Yi Lu;P. Gokulnath;Gururaja Vulugundam;Junjie Xiao
Cardiac aging is accompanied by progressive loss of cellular function, leading to impaired heart function and heart failure. There is an urgent need for efficient strategies to combat this age-related cardiac dysfunction. A growing number of events suggest that age-related cardiac diseases are tightly related to metabolic imbalance. This review summarizes recent findings concerning metabolic changes during cardiac aging and highlights the therapeutic approaches that target metabolic pathways in cardiac aging.
