Assessment of tuberculosis treatment completion in an ethnically diverse population using two data sources - Implications for treatment interventions
Assessment of tuberculosis treatment completion in an ethnically diverse population using two data sources - Implications for treatment interventions
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DOI：
10.1177/0163278702250080
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发表时间：
2003-03-01
影响因子：
2.9
通讯作者：
Kominski, G
中科院分区：
文献类型：
--
作者：
Morisky, DE;Ebin, VJ;Kominski, G
许多青少年被开了结核病(TB)感染的处方药，但未能完成治疗。本文介绍了对青少年人群结核病治疗完成率的人口统计学和流行病学评估结果，评估方法包括：(A)来自洛杉矶卫生局的监测数据；(B)来自目标诊所的前瞻性/回溯性医疗图表审查。未完成6个月隐匿性结核病治疗(LTBI)推荐内科治疗的患者平均接受治疗13周。年龄较小(OR=1.15；95%可信区间1.03-1.29)、出生在美国(OR=1.92；95%可信区间1.14-3.22，与墨西哥相比)和亚裔种族与完成护理相关。在多元Logistic回归分析中，年龄(OR=.88；95%CI.78-.98)和拉丁裔种族(OR=.53；95%CI.29-.95)仍然是完成治疗的重要预测因素。这些发现表明，在完成对LTBI的护理时，需要针对特定年龄的教育加强和文化差异。
Many adolescents who are prescribed therapy for tuberculosis (TB) infection fail to complete it. This article presents the results of a demographic and epidemiological assessment of TB treatment completion in adolescent populations using (a) surveillance data from the Los Angeles Health County Department and (b) a prospective/retrospective medical chart review from targeted clinics. Patients who did not complete the 6-month recommended medical treatment for latent tuberculosis therapy (LTBI) averaged 13 weeks in care. Younger age (OR = 1.15; 95% CI 1.03-1.29), birth in the United States (OR = 1.92; 95% CI 1.14-3.22, compared to Mexico), and Asian ethnicity were associated with completion of care. In multiple logistic regression analysis, age (OR = .88; 95% CI .78-.98) and Latino ethnicity (OR = .53; 95% CI .29-.95) remained significant predictors of completion of treatment. These findings indicate the need for age-specific educational reinforcement and cultural differentials in completing care for LTBI.