Quantitative Comparison of Retinal Vascular Features in Optical Coherence Tomography Angiography Images From Three Different Devices
Quantitative Comparison of Retinal Vascular Features in Optical Coherence Tomography Angiography Images From Three Different Devices
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DOI：
10.3928/23258160-20180628-04
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发表时间：
2018-07-01
影响因子：
1
通讯作者：
Roy, Abhijit Sinha
中科院分区：
文献类型：
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作者：
Anegondi, Neha;Kshirsagar, Arpita;Roy, Abhijit Sinha
背景和目的：比较三种不同设备的光学相干断层血管成像(OCTA)图像。材料和方法：这是一项前瞻性、观察性、横断面研究。所有患者(n=24)均采用扫描源OCT(DRI OCT Triton Plus；Topcon，日本东京)、光谱域OCTA(AngioVue；Optovue，弗里蒙特，加利福尼亚州)和SD-OCT Angiopex(Cirrus HD-OCT 5000；Carl Zeiss Meditec，德国耶拿)进行三次成像。观察指标为中心凹无血管区(FAZ)面积、血管密度、大血管间距(SLV)和小血管间距(SSV)。结果：三种装置的血管参数重复性良好(组内系数为0.8)。两种装置的FAZ面积(P=0.3)和浅层血管密度(P=0.8)相似。在深层，使用AngioVue图像的血管密度明显高于使用其他设备获取的血管密度(P=0.02)。而SLV显著高于对照组(P
BACKGROUND AND OBJECTIVE: To compare optical coherence tomography angiography (OCTA) images from three different devices.PATIENTS AND METHODS: This was a prospective, observational, cross-sectional study. All eyes (n = 24) were imaged thrice each time with swept-source OCT (DRI OCT Triton Plus; Topcon, Tokyo, Japan), spectral-domain OCTA (AngioVue; Optovue, Fremont, CA), and SD-OCT Angioplex (Cirrus HD-OCT 5000; Carl Zeiss Meditec, Jena, Germany). Outcome measures were foveal avascular zone (FAZ) area, vessel density, spacing between large vessels (SLV), and spacing between small vessels (SSV). They were calculated using local fractal analyses and Frangi filter.RESULTS: The vascular parameters showed good to excellent repeatability (intraclass coefficient > 0.8) in the three devices. The FAZ area (P=.3) and vessel density of the superficial layer (P=.8) were similar between the devices. In the deep layer, vessel density was significantly higher (P=.02) with AngioVue images compared to those acquired using the other devices. However, SLV was significantly higher (P