CRITERIA FOR DIAGNOSING PARKINSONS-DISEASE
CRITERIA FOR DIAGNOSING PARKINSONS-DISEASE
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DOI：
10.1002/ana.410320721
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发表时间：
1992-01-01
影响因子：
11.2
通讯作者：
LEE, C
中科院分区：
文献类型：
--
作者：
CALNE, DB;SNOW, BJ;LEE, C
帕金森氏病进展缓慢，目前有兴趣探索该疾病的早期阶段，因为研究发病机制和开发潜在的神经保护治疗的新方法。识别早期帕金森氏症并非易事。随着疾病的发展，诊断的确定性增加。为了解决帕金森氏病在临床表现的初始阶段被识别的问题，我们提出了以下诊断的指定置信度：(1)临床可能，(2)临床可能，和(3)临床确定。实验室对诊断的支持可能适用于每一类。提供的标准是支持这一分类的框架。
Parkinson's disease evolves slowly, and there is current interest in exploring the earliest stages of the disorder, because of new approaches to studying pathogenesis and developing potential neuroprotective treatment. Recognizing early Parkinson's disease is not easy. The certainty of diagnosis increases as the disease advances. To address the problem of identifying Parkinson's disease in its initial phases of clinical expression, we propose the following designated levels of confidence for the diagnosis: (1) clinically possible, (2) clinically probable, and (3) clinically definite. Laboratory support for the diagnosis may be applied to each category. Criteria are provided as a framework underpinning this classification.