Experimental support for an immunological approach to the search for life on other planets.
Experimental support for an immunological approach to the search for life on other planets.
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为在其他行星上寻找生命的免疫学方法提供实验支持。
DOI：
10.1089/ast.2005.5.30
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发表时间：
2005
期刊：
影响因子：
4.2
通讯作者：
S. Pincus
中科院分区：
文献类型：
--
作者：
M. Schweitzer;J. Wittmeyer;R. Avci;S. Pincus
我们提出了一种三阶段方法来测试外星样本中生命的证据。该方法利用了抗体-抗原相互作用的灵活性、敏感性和特异性。提供的数据支持第一阶段，其中比较了各种提取方案的效率，并针对各种抗原测试了一套初步的抗体。抗原和抗体的选择基于旨在优化活体或曾经活体生物体特有的外星生物标志物检测的标准。
We propose a three-phase approach to test for evidence of life in extraterrestrial samples. The approach capitalizes on the flexibility, sensitivity, and specificity of antibody-antigen interactions. Data are presented to support the first phase, in which various extraction protocols are compared for efficiency, and in which a preliminary suite of antibodies are tested against various antigens. The antigens and antibodies were chosen on the basis of criteria designed to optimize the detection of extraterrestrial biomarkers unique to living or once-living organisms.