VERTEBRATE EYE LENS

VERTEBRATE EYE LENS
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DOI:
10.1126/science.877544
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发表时间:
1977-01-01
期刊:
影响因子:
56.9
通讯作者:
BLOEMENDAL, H
BLOEMENDAL, H
中科院分区:
综合性期刊1区
文献类型:
--
作者:
BLOEMENDAL, H

文献摘要

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脊椎动物(人类和动物)的眼晶状体代表了一种不寻常但有效的组织,用于阐明许多具有代表性的生物过程。高度特异的聚合蛋白。-晶体蛋白,其命运,在合成后,可以跟随翻译后修饰和自组装进行了讨论。该蛋白是所有哺乳动物的主要成分,易于纯化,非常适合于氨基酸序列的比较研究。
The vertebrate eye lens [human and animal] represents an unusual but efficient tissue for the elucidation of a number of representative biological processes. The highly specific, polymeric protein, .alpha.-crystallin, whose fate, after synthesis, can be followed by posttranslational modifications and self-assembly was discussed. This protein, a major constitutent of all mammalian species, can easily by purified and is very suitable for comparative studies of amino acid sequences.