Periodontitis Is Associated with Chronic Obstructive Pulmonary Disease

Periodontitis Is Associated with Chronic Obstructive Pulmonary Disease
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DOI:
10.1177/0022034519833630
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发表时间:
2019-05-01
影响因子:
7.6
通讯作者:
Yamashita, Y.
Yamashita, Y.
中科院分区:
医学1区
文献类型:
--
作者:
Takeuchi, K.;Matsumoto, K.;Yamashita, Y.

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虽然它们被称为共享的病理生理过程,牙周炎和慢性阻塞性肺疾病(COPD)之间的关系还没有完全理解。本研究的目的是检验假设,牙周炎是与一个更大的风险发展的慢性阻塞性肺病,吸烟时考虑。一项5年随访人群队列研究的分析基于900名60岁或以上、至少有1颗牙齿的无COPD的社区居住日本成年人(年龄:68.8 ± 6.3 [平均值± SD],46.0%为男性)。参与者根据基线牙周炎严重程度分为3类(无/轻度、中度和重度)。COPD是通过呼吸量测定确定的一个固定比率,
Although they are known to share pathophysiological processes, the relationship between periodontitis and chronic obstructive pulmonary disease (COPD) is not fully understood. The aim of the present study was to test the hypothesis that periodontitis is associated with a greater risk of development of COPD, when smoking is taken into account. The analysis in a 5-y follow-up population-based cohort study was based on 900 community-dwelling Japanese adults (age: 68.8 +/- 6.3 [mean +/- SD], 46.0% male) without COPD aged 60 or older with at least 1 tooth. Participants were classified into 3 categories according to baseline periodontitis severity (no/mild, moderate, and severe). COPD was spirometrically determined by a fixed ratio of