Validation of shear wave elastography in skeletal muscle.
Validation of shear wave elastography in skeletal muscle.
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DOI：
10.1016/j.jbiomech.2013.07.033
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发表时间：
2013-09-27
影响因子：
2.4
通讯作者：
An, Kai-Nan
中科院分区：
文献类型：
--
作者：
Eby, Sarah F.;Song, Pengfei;Chen, Shigao;Chen, Qingshan;Greenleaf, James F.;An, Kai-Nan
骨骼肌是一种非常动态的组织，因此在其整个功能范围内准确量化骨骼肌硬度对于改善病理后的身体功能和独立性至关重要。剪切波弹性成像 (SWE) 是一种基于超声波的技术，可根据远程感应剪切波的传播来表征组织机械特性。本研究的目的是验证三个超声换能器方向的骨骼肌运动功能范围内的 SWE。我们假设，将传统材料测试 (MTS) 技术与 SWE 测量相结合，将显示出随着拉伸载荷的增加而增加的刚度测量值，并且在传感器平行于底层肌肉纤维的试验中彼此之间具有良好的相关性。为了评估这一假设，我们监测了四个猪肱肌全肌肉组织样本在整个拉伸负载过程中的变形，同时对同一样本进行了 SWE 测量。我们使用回归来检查每个换能器方向的 MTS 杨氏模量和 SWE 剪切模量之间的相关性。我们应用广义线性模型来解释重复测试。模型参数通过广义估计方程估计。平行传感器试验的回归系数为 0.1944，95% 置信区间为 (0.1463 – 0.2425)。剪切波对于 45° 和垂直换能器方向都不能很好地传播。平行的 SWE 和 MTS 都显示出随着拉伸载荷的增加而增加的刚度。这项研究为评估整个肌肉的刚度分布的其他研究提供了必要的第一步。
Skeletal muscle is a very dynamic tissue, thus accurate quantification of skeletal muscle stiffness throughout its functional range is crucial to improve the physical functioning and independence following pathology. Shear wave elastography (SWE) is an ultrasound-based technique that characterizes tissue mechanical properties based on the propagation of remotely induced shear waves. The objective of this study is to validate SWE throughout the functional range of motion of skeletal muscle for three ultrasound transducer orientations. We hypothesized that combining traditional materials testing (MTS) techniques with SWE measurements will show increased stiffness measures with increasing tensile load, and will correlate well with each other for trials in which the transducer is parallel to underlying muscle fibers. To evaluate this hypothesis, we monitored the deformation throughout tensile loading of four porcine brachialis whole-muscle tissue specimens, while simultaneously making SWE measurements of the same specimen. We used regression to examine the correlation between Young's modulus from MTS and shear modulus from SWE for each of the transducer orientations. We applied a generalized linear model to account for repeated testing. Model parameters were estimated via generalized estimating equations. The regression coefficient was 0.1944, with a 95% confidence interval of (0.1463 – 0.2425) for parallel transducer trials. Shear waves did not propagate well for both the 45° and perpendicular transducer orientations. Both parallel SWE and MTS showed increased stiffness with increasing tensile load. This study provides the necessary first step for additional studies that can evaluate the distribution of stiffness throughout muscle.
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影响因子：
3.4
作者：
Debernard, Laetitia;Robert, Ludovic;Bensamoun, Sabine F.
通讯作者：
Bensamoun, Sabine F.
影响因子：
5.5
作者：
Herbert, RD;Moseley, AM;Gandevia, SC
通讯作者：
Gandevia, SC
影响因子：
2.4
作者：
Gennisson, JL;Cornu, C;Portero, P
通讯作者：
Portero, P
DOI：
10.1098/rspb.1938.0050
发表时间：
1938-10-01
期刊：
PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES
影响因子：
--
作者：
Hill, AV
通讯作者：
Hill, AV
影响因子：
2.8
作者：
Brown, M;Fisher, JS;Salsich, G
通讯作者：
Salsich, G