Oxytocin responsivity in mothers of infants: a preliminary study of relationships with blood pressure during laboratory stress and normal ambulatory activity.
Oxytocin responsivity in mothers of infants: a preliminary study of relationships with blood pressure during laboratory stress and normal ambulatory activity.
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DOI：
10.1037//0278-6133.19.6.560
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
K. Light;Tara E. Smith;J. Johns;K. Brownley;J. Hofheimer;J. A. Amico
中科院分区：
文献类型：
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作者：
K. Light;Tara E. Smith;J. Johns;K. Brownley;J. Hofheimer;J. A. Amico
神经肽催产素 (OT) 可以增强母性行为，降低动物血压 (BP) 和应激反应。因此，我们对 14 名母乳喂养和 11 名奶瓶喂养婴儿的母亲的 OT 反应性与血压的关系进行了研究。在 2 天的基线、言语准备、主动言语和恢复期间评估实验室血压，其中 1 天基线和言语相隔 10 分钟的婴儿抱着时间，另一天没有婴儿接触。婴儿接触后，收缩压对言语的反应性较低。婴儿接触后血浆 OT 从基线到言语的变化定义了 OT 增加、最小 OT 变化和 OT 减少组。工作时间增加的母亲主要是母乳喂养者，与工作时间减少的母亲相比，她们在压力训练期间和在家喂养婴儿后的血压较低，而工作时间减少的母亲对准备和恢复的血压反应也更大。这些结果表明催产素对人类具有抗应激和降血压作用。
The neuropeptide oxytocin (OT) enhances maternal behavior and decreases blood pressure (BP) and stress responses in animals. Thus, the relationship of OT responsivity to BP in 14 breast- and 11 bottle-feeding mothers of infants was examined. Laboratory BP was assessed during baseline, speech preparation, active speech, and recovery on 2 days, 1 in which baseline and speech were separated by 10 min of baby holding and the other by no baby contact. Systolic BP reactivity to speech was lower after baby contact. Plasma OT change from baseline to speech after baby contact defined OT increase, minimal OT change, and OT decrease groups. OT increase mothers were primarily breast-feeders, and they had lower BP throughout both stress sessions and after baby feeding at home than OT decrease mothers, who also had greater BP reactivity to preparation and recovery. These results suggest that oxytocin has antistress and BP-lowering effects in humans.