Association of mitochondrial function and feed efficiency in poultry and livestock species
Association of mitochondrial function and feed efficiency in poultry and livestock species
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DOI：
10.2527/jas.2008-1379
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发表时间：
2009-04-01
影响因子：
3.3
通讯作者：
Carstens, G. E.
中科院分区：
文献类型：
--
作者：
Bottje, W. G.;Carstens, G. E.
随着谷物价格在过去一年中急剧上涨，了解饲料效率的基本遗传，细胞和生化机制（FE; g增重/g饲料）或剩余采食量（RFI;一种替代饲料效率性状，量化了体重和生长速率差异无法解释的体重差异的动物间差异）在家畜和家禽中，对于维持美国可行的肉类生产实践极其重要。虽然品种和饮食长期以来一直被认为会影响线粒体功能，但很少有研究调查由于FE或RFI的动物间表型差异而导致的线粒体功能和生物化学差异（即，同一品种的动物之间的差异，并喂食相同的饮食）。本文综述了家禽和家畜的线粒体功能和生化与FE和RFI的关系。本文的总体目标是帮助开发工具（例如，遗传标记或生物标志物），以帮助商业育种公司进行遗传选择，这反过来又将有助于维持美国和世界各地的畜牧业和家禽业。
As grain prices have increased dramatically in the past year, understanding the fundamental genetic, cellular, and biochemical mechanisms responsible for feed efficiency (FE; g of gain/g of feed) or residual feed intake (RFI; an alternative feed efficiency trait that quantifies interanimal variation in DMI that is unexplained by differences in BW and growth rate) in livestock and poultry is extremely important with respect to maintaining viable meat production practices in the United States. Although breed and diet have long been known to affect mitochondrial function, few studies have investigated differences in mitochondrial function and biochemistry due to interanimal phenotypic differences in FE or RFI (i.e., variation among animals of the same breed and fed the same diet). This paper reviews existing literature on relationships of mitochondrial function and biochemistry with FE and RFI in poultry and livestock. The overall goal of all of this paper is to assist the development of tools (e.g., genetic markers or biomarkers) to aid commercial breeding companies in genetic selection that, in turn, will help maintain viable livestock and poultry industries in the United States and around the world.