Thiolated gamma-cyclodextrin-polymer-functionalized CeFe3O4 magnetic nanocomposite as an intrinsic nanocatalyst for the selective and ultrasensitive colorimetric detection of triacetone triperoxide.
Thiolated gamma-cyclodextrin-polymer-functionalized CeFe3O4 magnetic nanocomposite as an intrinsic nanocatalyst for the selective and ultrasensitive colorimetric detection of triacetone triperoxide.
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DOI：
10.1016/j.chemosphere.2022.136108
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发表时间：
2022-08
期刊：
影响因子：
8.8
通讯作者：
M. L. Nsuamani;S. Zolotovskaya;A. Abdolvand;N. Daéid;Oluwasesan Adegoke
中科院分区：
文献类型：
--
作者：
M. L. Nsuamani;S. Zolotovskaya;A. Abdolvand;N. Daéid;Oluwasesan Adegoke
爆炸物是地球仪各地犯罪分子和恐怖分子使用的强大毁灭性武器，在军事设施场地使用爆炸物造成严重的环境卫生问题。现有的三过氧化三丙酮（TATP）比色传感器依赖于检测其水解的H2 O2形式。然而，这样的检测策略限制了现场TATP感测的实用性。在这项工作中，我们开发了一种新的过氧化物酶模拟催化比色传感器直接识别TATP。在金属前驱体和有机配体的存在下，采用热注入有机合成法合成了CeO 2（Ce）掺杂的Fe 3 O 4纳米粒子（CeFe 3 O 4）。之后，有机封端的CeFe 3 O 4纳米粒子的表面功能化的两亲性聚合物（Amp聚），使纳米粒子稳定，紧凑和生物相容性。将巯基化γ-环糊精（γ-CD）吸附在Amp-聚CeFe 3 O 4纳米复合材料（NC）表面，形成γ-CD-poly-CeFe 3 O 4 NC。γ-CD既是TATP的受体，又是催化增强剂。以氯化血红素（H）为催化信号放大剂，将其吸附在γ-CD-poly-CeFe 3 O 4-NC表面，形成γ-CD-poly-CeFe 3 O 4-H NC纳米酶，用于TATP的增强催化比色检测。在最佳实验条件下，基于γ-CD-Amp-poly-CeFe 3 O 4-H混合纳米酶催化H2 O2氧化3，3 '，5，5'-四甲基联苯胺，在BIS-TRIS-Trisma Ac-KAc-NAc缓冲液（pH 3）中制备的TATP无需酸解即可选择性超灵敏检测。与其他已发表的探针相比，获得的检测限为10.05 μg/mL，表现出优越的上级灵敏度。研制的过氧化物酶模拟γ-CD-Amp-poly-CeFe 3 O 4-H催化比色传感器成功应用于土壤、河水和自来水样品中TATP的检测。
Explosives are powerful destructive weapons used by criminals and terrorists across the globe and their use within military installation sites poses serious environmental health problems. Existing colorimetric sensors for triacetone triperoxide (TATP) relies on detecting its hydrolysed H2O2form. However, such detection strategy limits the practicability for on-site TATP sensing. In this work, we have developed a novel peroxidase mimic catalytic colorimetric sensor for direct recognition of TATP. Ceria (Ce)-doped Fe3O4nanoparticles (CeFe3O4) were synthesized via the hot-injection organic synthetic route in the presence of metal precursors and organic ligands. Thereafter, the organic-capped CeFe3O4nanoparticles were surface-functionalized with amphiphilic polymers (Amp-poly) to render the nanoparticle stable, compact and biocompatible. Thiolated γ-cyclodextrin (γ-CD) was adsorbed on the Amp-poly-CeFe3O4nanocomposite (NC) surface to form a γ-CD-Amp-poly-CeFe3O4NC. γ-CD served both as a receptor and as a catalytic enhancer for TATP. Hemin (H), used as a catalytic signal amplifier was adsorbed on the γ-CD-Amp-poly-CeFe3O4NC surface to form a γ-CD-Amp-poly-CeFe3O4–H NC that served as a functional nanozyme for the enhanced catalytic colorimetric detection of TATP. Under optimum experimental reaction conditions, TATP prepared in BIS-TRIS-Trisma Ac-KAc-NAc buffer, pH 3, was selectively and ultrasensitively detected without the need for acid hydrolysis based on the catalytic oxidation of 3,3′,5,5′-tetramethylbenzidine by H2O2in the presence of the γ-CD-Amp-poly-CeFe3O4–H hybrid nanozyme. The obtained limit of detection of ∼0.05 μg/mL when compared with other published probes demonstrated superior sensitivity. The developed peroxidase mimic γ-CD-Amp-poly-CeFe3O4–H catalytic colorimetric sensor was successfully applied to detect TATP in soil, river water and tap water samples.