Physiological pulsatile flow experiments in a model of the human aortic arch.
Physiological pulsatile flow experiments in a model of the human aortic arch.
复制标题
人体主动脉弓模型中的生理脉动流实验。
DOI：
10.1016/0021-9290(82)90023-9
复制
发表时间：
1982
影响因子：
2.4
通讯作者：
K. B. Chandran
中科院分区：
文献类型：
--
作者：
T. Yearwood;K. B. Chandran
在人体主动脉弓模型中进行了与生理相关的脉动流的实验研究。主动脉弓流动室模型由人主动脉的原位铸造制成，并被纳入模拟循环系统中。该模型排除了冠状窦和中弓区域的三个主要分支动脉，以便仅集中于主动脉中的多维曲率和锥形的影响。此外，在流动室上游放置了一个流动矫直部分，以消除这些研究中使用的人工主动脉瓣产生的任何流体扰动。在模型主动脉中的定性流动可视化研究揭示了在内壁附近存在强烈的二次流体运动。这些螺旋流在心脏舒张期间消散，受到心脏舒张开始时沿着内壁发生的剧烈血流逆转的极大影响。使用三传感器热膜速度探头进行定量研究，以确定在主动脉中的各个横截面处的轴向、径向和切向速度分量。结果表明，在涡孔形成初期，靠近内壁的轴向速度发生了急剧的反转。
An experimental investigation of physiologically relevant pulsatile flow in a model of the human aortic arch has been conducted. The model aortic arch flow chamber was fabricated in clear acrylic from anin situcasting of the human aorta and was incorporated in a mock-circulatory system. The model excluded the coronary sinuses and the three major branching arteries of the mid-arch region in order to concentrate only upon the effects of the multi-dimensional curvatures and tapering in the aorta. Furthermore, a flow straightening section was placed upstream to the flow chamber to eliminate any fluid disturbances created by the prosthetic aortic valve used in these studies. The qualitative flow visualization studies in the model aorta revealed the presence of strong secondary fluid motions near the inner wall. These helical flows dissipated during diastole, being greatly affected by the dramatic flow reversals which occurred along the inner wall at the onset of diastole. Quantitative studies were conducted using a three-sensor hot-film velocity probe to determine the axial, radial and tangential velocity components at various cross-sections in the aorta. The results showed rapid reversal of axial velocity near the inner wall at the onset of diastole.