Session 1SCA?Utilizing soft compartments/interfaces for the creation of artificial biosystems
Session 1SCA?Utilizing soft compartments/interfaces for the creation of artificial biosystems
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会议 1SCA？利用软隔室/界面创建人工生物系统
DOI：
10.1007/s12551-020-00647-y
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发表时间：
2020
影响因子：
--
通讯作者：
Suzuki Yuki
中科院分区：
文献类型：
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作者：
Sato Yusuke;Morita Masamune;Suzuki Yuki
活细胞是由生物膜包围的自主分子系统，生物膜具有由脂质双层组成的柔软结构。在调节分子系统中具有关键作用的各种生化反应发生在细胞膜所包围的空间或膜的界面处。这些反应依赖于膜的各种性质，如流动性、表面电荷和蛋白质相互作用（Alberts et al. 2008）。揭示这种“软”隔室/界面特有的现象，不仅可以更好地理解生命系统，还可以设计更精确的人工生物系统。为此，我们在第57届日本生物物理学会年会上举办了题为“从纳米到宏观利用软隔室/界面：探索生命系统的潜力”的研讨会（图1）。这次研讨会的重点是软隔室和接口，即脂质囊泡的内部空间和脂质双层的表面，在几个层次，从分子到组织水平。我们邀请了两位演讲者，Yuno Natalie博士和Kaori Kuribayashi-Shigetomi博士，并选择了三位演讲者
A living cell is an autonomous molecular system surrounded by a biological membrane that possesses a soft structure composed of a lipid bilayer. Various biochemical reactions, which have crucial roles in regulating the molecular system, occur in the space surrounded by the cellular membrane or at the interface of the membrane. These reactions rely on various properties of the membrane, such as fluidity, surface charge, and protein interactions (Alberts et al. 2008). Unraveling phenomena specific to such “soft” compartments/interfaces will not only lead to a better understanding of living systems but will also allow the designing of more accurate artificial biosystems.We thus organized a symposium entitled “Utilization of soft compartments/interfaces from nano to macroscale: Exploring the potential of living systems” at the 57th annual meeting of Biophysical Society of Japan (Fig. 1). This symposium focused on soft compartments and interfaces, ie, the inner space of lipid vesicles and the surface of lipid bilayers, at several hierarchical levels, ranging from the molecular to the tissue level. We invited two speakers, Dr. Yuno Natsume and Dr. Kaori Kuribayashi-Shigetomi, and selected three speakers