Stille couplings catalytic in tin: A "Sn-F" approach
Stille couplings catalytic in tin: A "Sn-F" approach
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DOI：
10.1021/ol016792z
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发表时间：
2001-12-27
期刊：
影响因子：
5.2
通讯作者：
Gallagher, WP
中科院分区：
文献类型：
--
作者：
Maleczka, RE;Gallagher, WP
[图表]报道了一种新的锡回收方法，用于锡中的Stille偶联催化。由KF（aq）制成的超配位PMHS允许Me 3SnH在Pd（0）催化的锡氢化/Stille级联期间有效地再循环。相对于先前公开的方案，反应时间更短，并且因为该方法被认为通过Me 3SnF中间体进行，所以与三甲基锡相关的危险和问题也减少了。
[GRAPHICS]A new tin recycling method for Stille couplings catalytic in tin is reported. PMHS made hypercoordinate by KF(aq) allows Me3SnH to be efficiently recycled during a Pd(0)-catalyzed hydrostannation/Stille cascade. Relative to previously disclosed protocols, reaction times are shorter and because this process is believed to proceed through a Me3SnF intermediate the hazards and problems associated with trimethyltins are also diminished.