No Increased Risk of Taking Additional Intestinal Mucosal Research Biopsies From the Duodenum During Pediatric Endoscopy.
No Increased Risk of Taking Additional Intestinal Mucosal Research Biopsies From the Duodenum During Pediatric Endoscopy.
复制标题
在儿科内窥镜检查期间从十二指肠进行额外的肠粘膜研究活检不会增加风险。
DOI：
10.1097/mpg.0000000000003723
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发表时间：
2023
影响因子：
2.9
通讯作者：
Leonard,MaureenM
中科院分区：
文献类型：
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作者：
DaFonte,TraceyM;Gleeson,Elizabeth;Morson,Taylor;Olshan,KatherineL;Moran,ChristopherJ;Leonard,MaureenM
涉及人类肠道组织的研究对于推进乳糜泻（CeD）领域至关重要，因为诊断需要十二指肠活检。在儿童中进行研究有助于更好地了解这一重要亚群中的CeD。本研究旨在确定在小儿内镜检查中进行十二指肠研究活检的风险。在2016年至2022年1180名研究对象和对照组的回顾性图表回顾中，48小时内发生了18起与手术相关的不良事件。大多数不良事件为疼痛和发热症状。如果在儿童内窥镜检查期间进行额外的十二指肠研究活检，则不良事件的风险不会增加。
Studies involving human intestinal tissue are essential for advancing the field of celiac disease (CeD), as diagnosis requires duodenal biopsies. Performing studies in children helps to better understand CeD in this important subpopulation. This study aims to determine the risk in obtaining duodenal research biopsies during pediatric endoscopy. In this retrospective chart review from 2016 to 2022 of 1180 research subjects and controls, there were 18 procedure-related adverse events within 48 hours. Most adverse events were for symptoms of pain and fever. There was no increased risk of adverse events if additional duodenal research biopsies were taken during pediatric endoscopy.