Imaging the shear modulus of the heel fat pads
Imaging the shear modulus of the heel fat pads
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DOI：
10.1016/j.clinbiomech.2004.11.010
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发表时间：
2005-03-01
影响因子：
1.8
通讯作者：
Paulsen, K
中科院分区：
文献类型：
--
作者：
Weaver, JB;Doyley, M;Paulsen, K
背景。稳态、动态 MR 弹性成像可提供体内组织剪切模量的定量图像。评估了磁共振弹性成像表征体内承重足底软组织机械特性的能力。方法。当受试者对足部施加低压时以及当受试者施加高压时，使用磁共振弹性成像对足跟脂肪垫和周围软组织进行成像。两组图像的脚的位置是相同的。结果。结果与预期趋势非常吻合。随着压力的增加，跟骨下组织的剪切模量从8 kPa增加到12 kPa，而周围组织的剪切模量保持恒定在8 kPa，这与乳腺组织中脂肪的剪切模量相似。解释。正在开发的用于测量足底软组织剪切模量的稳态磁共振弹性成像方法的初步结果是有希望的。 MR 弹性成像足够准确，可以观察剪切模量随施加压力变化的变化，并且能够表征足底软组织的机械特性。详细的解剖信息可以与共同注册的机械特性相结合。磁共振弹性成像可以在了解足底软组织的承重功能和评估这些结构以改进疾病进展的诊断和评估方面发挥重要作用。 (C) 2004 年，爱思唯尔有限公司出版。
Background. Steady state, dynamic MR elastography provides quantitative images of the shear modulus of tissues in vivo. MR elastography was evaluated for its ability to characterize the mechanical properties of the weight bearing plantar soft tissues in vivo.Methods. MR elastography was used to image the heel fat pad and surrounding soft tissues when the subject applied a low pressure on the foot and again when the subject applied high pressure. The placement of the foot was identical for both sets of images.Findings. The results agree well with expected trends. The shear modulus of the tissue under the calcaneus increased from 8 kPa to 12 kPa with increasing pressure while that of peripheral tissues remained constant at 8 kPa which is similar to the shear modulus of fat in breast tissue.Interpretation. Preliminary results from the steady state MR elastography methods being developed to measure the shear modulus of plantar soft tissues are promising. MR elastography is sufficiently accurate to observe the change in shear modulus with changes in applied pressure and is capable of characterizing the mechanical properties of the plantar soft tissues. Detailed anatomic information can be combined with co-registered mechanical properties. MR elastography could play a significant role in understanding the weight bearing functions of the plantar soft tissues and in evaluating those structures for improved diagnosis and assessment of disease progression. (C) 2004 Published by Elsevier Ltd.