Involvement of human left frontoparietal cortices in neural processes associated with task-switching between two sequences of skilled finger movements
Involvement of human left frontoparietal cortices in neural processes associated with task-switching between two sequences of skilled finger movements
复制标题
人类左额顶皮质参与与两个熟练手指运动序列之间的任务切换相关的神经过程
DOI：
10.1016/j.brainres.2019.146365
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发表时间：
2019
期刊：
影响因子：
2.9
通讯作者：
Naito Eiichi
中科院分区：
文献类型：
--
作者：
Uehara Shintaro;Mizuguchi Nobuaki;Hirose Satoshi;Yamamoto Shinji;Naito Eiichi
在这项研究中，我们证明了参与左额顶叶皮质的神经过程之间的任务切换熟练的动作。32名右利手的健康参与者用左手进行两次连续的手指运动任务，同时进行功能性磁共振成像。一组（n = 16）通过随机练习（任务被切换或重复试验）在一天和块练习（每个任务的连续密集练习）在第二天训练这些任务，而其余的参与者以相反的顺序练习。在第一天，所有参与者的两项任务的表现都有所改善，这表明这两项技巧性任务可以在两个练习时间表中学习。然而，在随机练习中，在切换试验中的性能最初恶化，并逐渐接近在重复试验中的实践进行。左（主要是下）额顶叶皮层表现出更大的准备活动的切换试验相比，在左半球占主导地位的方式重复试验，和左顶内活动减少切换试验的性能提高。结果表明，任务转换的神经过程与更大的准备活动在左下额顶皮层，和有效的切换可能进行伴随着左顶内活动减少。
In this study, we demonstrate the involvement of left frontoparietal cortices in neural processes for task-switching between skilled movements. Functional magnetic resonance imaging was conducted while thirty-two right-handed healthy participants performed two sequential finger-movement tasks with their left hands. One group (n = 16) trained these tasks through random-practice (tasks were either switched or repeated trial by trial) on one day and blocked-practice (successive intensive practice of each task) on the next day, while the remaining participants practiced in the reverse order. On the first day, performance of both tasks improved in all participants, suggesting that the two skilful tasks can be learned in both practice schedules. However, during the random-practice, the performance in the switched trials initially deteriorated and gradually approached to that in the repeated trials as the practice proceeded. The left (mainly inferior) frontoparietal cortices showed greater preparatory activity for the switched trials compared with the repeated trials in a left-hemispheric dominant manner, and the left intraparietal activity decreased as the performance of the switched trials improved. The results indicate that neural processes for task-switching are associated with the greater preparatory activity in the left inferior frontoparietal cortices, and the efficient switching may proceed concomitantly with the left intraparietal activity reduction.