The dynamics of injection drug users' personal networks and HIV risk behaviors
The dynamics of injection drug users' personal networks and HIV risk behaviors
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DOI：
10.1111/j.1360-0443.2006.01431.x
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发表时间：
2006-07-01
期刊：
影响因子：
6
通讯作者：
Latkin, Carl A.
中科院分区：
文献类型：
--
作者：
Costenbader, Elizabeth C.;Astone, Nan M.;Latkin, Carl A.
目的虽然注射吸毒者（IDUs）的社交网络的研究提供了深入了解注射吸毒者之间的人际关系的结构如何影响艾滋病毒的危险行为，这些研究中的大多数是横截面。本研究考察了注射吸毒者社交网络和艾滋病毒危险行为随时间的动态变化。设计使用的数据从纵向艾滋病干预研究进行了巴尔的摩，MD，本研究评估了409注射吸毒者的个人网络的组成的变化。我们使用多项逻辑回归分析来评估网络组成的变化与注射HIV风险行为水平的同时变化之间的关联。使用由多项模型生成的回归参数，我们估计了四个HIV危险行为改变组中的每一个的预测概率。调查结果与基础病例相比，在随访时报告了一组全新的吸毒网络接触者属于风险增加组的可能性是其他人的三倍多。相比之下，在随访时报告所有新的非吸毒接触者，将处于稳定低风险组的可能性增加了近50%，并将处于持续高风险组的可能性降低了70%以上。结论本研究的结果表明，在静脉吸毒者的基线特征之上，他们的个人网络的变化与个人的危险注射行为的变化有关。他们还建议，增加注射吸毒者与非吸毒者的社会接触，可能有利于采取旨在减少注射吸毒者中艾滋病毒风险的干预措施。
Aims While studies of the social networks of injection drug users (IDUs) have provided insight into how the structures of interpersonal relationships among IDUs affect HIV risk behaviors, the majority of these studies have been cross-sectional. The present study examined the dynamics of IDUs' social networks and HIV risk behaviors over time. Design Using data from a longitudinal HIV-intervention study conducted in Baltimore, MD, this study assessed changes in the composition of the personal networks of 409 IDUs. We used a multi-nomial logistic regression analysis to assess the association between changes in network composition and simultaneous changes in levels of injection HIV risk behaviors. Using the regression parameters generated by the multi-nomial model, we estimated the predicted probability of being in each of four HIV risk behavior change groups. Findings Compared to the base case, individuals who reported an entirely new set of drug-using network contacts at follow-up were more than three times as likely to be in the increasing risk group. In contrast, reporting all new non-drug-using contacts at follow-up increased the likelihood of being in the stable low-risk group by almost 50% and decreased the probability of being in the consistently high-risk group by more than 70%. Conclusions The findings from this study show that, over and above IDUs' baseline characteristics, changes in their personal networks are associated with changes in individuals' risky injection behaviors. They also suggest that interventions aimed at reducing HIV risk among IDUs might benefit from increasing IDUs' social contacts with individuals who are not drug users.