Predictors of self-reported antidepressant adherence
Predictors of self-reported antidepressant adherence
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DOI：
10.3200/bmed.32.4.127-134
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发表时间：
2007-12-01
影响因子：
2.3
通讯作者：
Stewart, Donna E.
中科院分区：
文献类型：
--
作者：
Burra, Tara A.;Chen, Edmund;Stewart, Donna E.
本研究的目的是：（1）评估自我报告的抗抑郁药依从性水平和不依从的原因，（2）调查不依从的决定因素。一组综合医院和社区精神病学实践的心境障碍门诊患者（n = 80）采取了自我报告问卷，评估有关抗抑郁药的信念，自我效能和不遵守的原因。报告了高水平的依从性：58名患者（73%）表示他们在80%以上的时间内按照指示服用药物。实际问题（例如，仅仅是忘记或改变常规）是最常见的不依从原因。如果患者经历了性副作用，自我效能较低，则更有可能报告不依从。1999年至1999年期间，这些人均为女性，未完成中学后教育。临床医生应该认识到这种复杂性，不仅要解决与药物疗效和耐受性有关的问题，还要解决在开抗抑郁药时的社会中介和健康信念问题。
The authors' objectives of this research were: (1) to assess levels of self-reported antidepressant adherence and reasons for nonadherence and (2) to investigate determinants of nonadherence. A group of general hospital and community psychiatry practice mood disorder outpatients (n = 80) took a self-report questionnaire that assessed beliefs about antidepressants, self-efficacy, and reasons for nonadherence. High levels of adherence were reported: 58 patients (73%) indicated they took their medication as directed more than 80% of the time. Practical issues (e.g., simply forgetting or a change in routine) were the most frequently identified reasons for nonadherence. Patients were more likely to report nonadherence if they experienced a sexual side effect, had lower self-efficacy. were female, and had not completed post-secondary education. Clinicians should be cognizant of this complexity and address not only issues related to medication efficacy and tolerability, but also social mediators and health beliefs when prescribing antidepressants.