Variability in cerebral blood flow velocity: Observations over one minute in preterm babies
Variability in cerebral blood flow velocity: Observations over one minute in preterm babies
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DOI：
10.1016/s0378-3782(96)01769-0
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发表时间：
1997-01-03
影响因子：
2.5
通讯作者：
Evans, DH
中科院分区：
文献类型：
--
作者：
Coughtrey, H;Rennie, JM;Evans, DH
应用多普勒超声对连续入院的52例极低出生体重儿进行出生后第1天的脑血流速度（CBFV）测定。记录时间为1 min。计算20个连续心动周期曲线下面积的变异系数，然后将20个周期移动窗口应用于整个记录。这表明，任何个体在1分钟内的变异系数变化很大，范围为2%至28%（中位数为8%）。CBFV的变异性与体循环血压（BP）的变异性之间有很强的相关性。CBFV的变异性在癫痫发作的婴儿中显著更高（P = 0.026）。死亡婴儿的最大变异系数高于存活婴儿（P = 0.05），但我们无法证实与脑损伤或动脉导管未闭的任何关联。
Cerebral blood Bow velocity (CBFV) was measured using Doppler ultrasound on the first day of life in a consecutively admitted cohort of 52 very low birthweight infants. Recordings were made for a period of 1 min. The coefficient of variation for the area under the curve of 20 successive cardiac cycles was calculated, and a 20 cycle moving window then applied to the whole recording. This showed that the coefficient of variation varied widely during 1 min in any individual, the range being from 2% to 28% (median 8%). There was a strong correlation between the variability in CBFV and that in systemic blood pressure (BP). Variability in CBFV was significantly higher in babies with hypotensive episodes (P = 0.026). Babies who died had a higher maximum coefficient of variation than those who survived (P = 0.05), but we were unable to confirm any association with brain injury or patent ductus arteriosus.