Bayesian Emulation and History Matching of JUNE
Bayesian Emulation and History Matching of JUNE
复制标题
六月的贝叶斯仿真和历史匹配
DOI:
10.1101/2022.02.21.22271249
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发表时间:
2022
期刊:
影响因子:
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通讯作者:
Vernon I
中科院分区:
文献类型:
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作者:
Vernon I
We analyzeJUNE: a detailed model of COVID-19 transmission with high spatial and demographic resolution, developed as part of the RAMP initiative.JUNErequires substantial computational resources to evaluate, making model calibration and general uncertainty analysis extremely challenging. We describe and employ the uncertainty quantification approaches of Bayes linear emulation and history matching to mimicJUNEand to perform a global parameter search, hence identifying regions of parameter space that produce acceptable matches to observed data, and demonstrating the capability of such methods.This article is part of the theme issue ‘Technical challenges of modelling real-life epidemics and examples of overcoming these’.