ES-6, A FURTHER POLYMORPHIC ESTERASE IN THE RAT

ES-6, A FURTHER POLYMORPHIC ESTERASE IN THE RAT
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DOI:
10.1007/bf00484420
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发表时间:
1982-01-01
影响因子:
2.4
通讯作者:
GUNTHER, E
GUNTHER, E
中科院分区:
生物学4区
文献类型:
--
作者:
BENDER, K;NAGEL, M;GUNTHER, E

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进一步的多态性大鼠酯酶与广泛的组织表达和限制底物特异性的描述和暂定为Es-6。近交系大鼠品系具有固定等位基因Es-6 F或固定等位基因Es-6S。Es-6不与大鼠LG [连锁群] V中由8个酯酶位点Es-1、Es-2、Es-3 M、Es-4 M、Es-4 W、Es-5(=Es-3 W)、Es-7和Es-8组成的已建立的酯酶簇连锁,也不与RT 1、Gc、c、a和h连锁。具有明显相同的生化和遗传特征的酯酶是小鼠的Es-17和人的Es-A4。
A further polymorphic rat esterase with broad tissue expression and restricted substrate specificity is described and tentatively called Es-6. Inbred rat strains have either fixed allele Es-6F or fixed allele Es-6S. Es-6 is not linked to the established esterase cluster consisting of the 8 esterase loci Es-1, Es-2, Es-3M, Es-4M, Es-4W, Es-5 (=Es-3W), Es-7 and Es-8 in LG [linkage group] V of the rat or to RT1, Gc, c, a and h. Esterases with apparently identical biochemical and genetical characteristics are Es-17 of the mouse and Es-A4 of humans.