Humor Appreciation Involves Parametric and Synchronized Activity in the Medial Prefrontal Cortex and Hippocampus
Humor Appreciation Involves Parametric and Synchronized Activity in the Medial Prefrontal Cortex and Hippocampus
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DOI：
10.1093/cercor/bhw325
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发表时间：
2017-12-01
期刊：
影响因子：
3.7
通讯作者：
Iidaka, Tetsuya
中科院分区：
文献类型：
--
作者：
Iidaka, Tetsuya
幽默感是人类社会中普遍存在的现象。在幽默感知理论中，幽默涉及三个因素：不严肃、社会背景和不协调。然而，在另一种理论中，对情境的阐述和重新解释被认为在引发幽默方面发挥着作用。尽管已经使用神经影像学方法研究了幽默欣赏的神经相关性，但只有少数研究在自然条件下进行了此类实验。在本研究中，使用喜剧电影作为刺激进行了两项功能性磁共振成像实验，以研究自然条件下幽默的神经相关性。研究人员在观看和欣赏电影时测量了受试者的大脑活动。在实验1中，参数分析表明内侧前额叶皮层（MPFC）和海马/杏仁核与主观搞笑度评分呈正相关。在实验 2 中，分析了受试者间相关性以调查所有参与者的同步活动。在 MPFC 和海马体中观察到与搞笑等级增加平行的信号同步。因此，MPFC 和海马体中的参数和同步活动似乎在幽默欣赏过程中都很重要。本研究揭示了自然条件下主要参与幽默感的大脑区域。
Humor perception is a ubiquitous phenomenon in human societies. In theories of humor perception, three factors, non-seriousness, social context, and incongruity, have been implicated in humor. In another theory, however, elaboration and reinterpretation of contexts are considered to play a role in eliciting humor. Although the neural correlates of humor appreciation have been investigated using neuroimaging methods, only a few studies have conducted such experiments under natural conditions. In the present study, two functional magnetic resonance imaging experiments, using a comedy movie as a stimulus, were conducted to investigate the neural correlates of humor under natural conditions. The subjects' brain activity was measured while watching and enjoying a movie. In experiment 1, a parametric analysis showed that the medial prefrontal cortex (MPFC) and hippocampus/amygdala had a positive relationship with the subjective rating of funniness. In experiment 2, intersubject correlation was analyzed to investigate synchronized activity across all participants. Signal synchronization that paralleled increased funniness ratings was observed in the MPFC and hippocampus. Thus, it appears that both parametric and synchronized activity in the MPFC and hippocampus are important during humor appreciation. The present study has revealed the brain regions that are predominantly involved in humor sensation under natural condition.