Gold-Catalyzed Stereoselective Synthesis of Azacyclic Compounds through a Redox/[2+2+1] Cycloaddition Cascade of Nitroalkyne Substrates
Gold-Catalyzed Stereoselective Synthesis of Azacyclic Compounds through a Redox/[2+2+1] Cycloaddition Cascade of Nitroalkyne Substrates
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DOI：
10.1021/ja110514s
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发表时间：
2011-02-16
影响因子：
15
通讯作者：
Liu, Rai-Shung
中科院分区：
文献类型：
--
作者：
Jadhav, Appaso Mahadev;Bhunia, Sabyasachi;Liu, Rai-Shung
We report a new redox/cycloaddition cascade on readily available 1-alkynyl-2-nitrobenzenes that produces complex azacyclic compounds stereoselectively. The core structures of the resulting products are constructed through a formal [2 + 2 + 1] cycloaddition among a-carbonyl carbenoids, nitroso species, and external alkenes.
