Influence of Diphenylhydantoin and Phenobarbital on Intestinal Calcium Transport in the Rat *
Influence of Diphenylhydantoin and Phenobarbital on Intestinal Calcium Transport in the Rat *
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二苯乙内酰脲和苯巴比妥对大鼠肠道钙转运的影响*
DOI：
10.1111/j.1528-1157.1972.tb05167.x
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发表时间：
1972
期刊：
影响因子：
5.6
通讯作者：
K. Schaefer
中科院分区：
文献类型：
--
作者：
H. Koch;D. Kraft;D. Herrath;K. Schaefer
In vitamin D deficient rats the influence of diphenylhydantoin (DPH) and phénobarbital (PB) pretreatment on intestinal uptake of 45calcium and on the activity of CaBP was studied. The DPH rats show in contrast to the PB and control rats a significantly reduced intestinal uptake of 45calcium. However, the activity of CaBP was similar in all investigated groups. These results suggest a possibly special effect of DPH on the development of the calcium and bone disorders that have been observed in patients treated with anticonvulsant drugs.
