Birth weight, rapid weight gain in infancy and markers of overweight and obesity in childhood
Birth weight, rapid weight gain in infancy and markers of overweight and obesity in childhood
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DOI：
10.1038/ejcn.2013.183
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发表时间：
2013-11-01
影响因子：
4.7
通讯作者：
Rondo, P. H. C.
中科院分区：
文献类型：
--
作者：
Sacco, M. R.;de Castro, N. P.;Rondo, P. H. C.
目的：使用不同的快速体重增加临界值，评估出生体重和婴儿期体重快速增加以及儿童期超重/肥胖标志物之间的关系。 对象/方法：对 98 名 5 岁学龄前巴西儿童进行横断面研究。体重快速增加被认为是在出生后 2 年内的任何时间，标准差评分 (SDS) 相对于出生体重的体重增加超过 + 0.67、+ 1 和 + 2。通过人体测量学和生物电阻抗来确定儿童的营养状况。采用多元线性回归分析，将脂肪质量百分比、体重指数（BMI）、腰围和颈围作为结果。 结果：出生体重、体重快速增加（通过不同的临界值评估）和产妇肥胖与脂肪质量百分比、BMI、腰围和颈围的增加呈正相关。不同的快速增重截止值并没有改变快速增重与脂肪质量百分比之间的正相关关系（> + 0.67 SDS，P=0.007；> + 1 SDS，P=0.007；> + 2 SDS，P=0.01）、BMI（> + 0.67 SDS，P=0.002；> +1 SDS，P=0.007；> +2 SDS，P + 0.67 SDS，P=0.002；>+1 SDS，P=0.002；>+2 SDS，P+0.01；>+1 SDS，P=0.03；
OBJECTIVE: To evaluate the relationship between birth weight and rapid weight gain in infancy and markers of overweight/obesity in childhood, using different cutoff values for rapid weight gain.SUBJECTS/METHODS: Cross-sectional study involving 98 5-year old pre-school Brazilian children. Rapid weight gain was considered as weight gain in standard deviation score (SDS) above + 0.67, + 1 and + 2 in relation to birth weight, at any time during the first 2 years of life. The nutritional status of the children was determined by anthropometry and electrical bioimpedance. Multiple linear regression analysis was used, considering fat mass percentage, body mass index (BMI), waist and neck circumferences as outcomes.RESULTS: Birth weight, rapid weight gain (assessed by different cutoff values) and maternal obesity were positively associated with increased fat mass percentage, BMI, waist and neck circumferences. Different cutoff values of rapid weight gain did not change the positive associations between rapid weight gain and fat mass percentage (> + 0.67 SDS, P=0.007; > + 1 SDS, P=0.007; > + 2 SDS, P=0.01), BMI (> + 0.67 SDS, P=0.002; > +1 SDS, P=0.007; > +2 SDS, P + 0.67 SDS, P=0.002; > +1 SDS, P=0.002; > +2 SDS, P + 0.67 SDS, P=0.01; > + 1 SDS, P=0.03; > +2 SDS, P