The effect of cinnamon on A1C among adolescents with type 1 diabetes

The effect of cinnamon on A1C among adolescents with type 1 diabetes
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DOI:
10.2337/dc06-1871
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发表时间:
2007-04-01
期刊:
影响因子:
16.2
通讯作者:
Curtis, Kevin M.
Curtis, Kevin M.
中科院分区:
医学1区
文献类型:
--
作者:
Altschuler, Justin A.;Casella, Samuel J.;Curtis, Kevin M.

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目的:本研究的目的是确定肉桂对青少年I型糖尿病患者血糖控制的影响。研究设计和方法:采用前瞻性、双盲、安慰剂对照设计,72名青少年I型糖尿病患者在门诊接受肉桂(1 g/天)或等效安慰剂治疗90天。记录AlC、每日总胰岛素摄入量和不良事件,并进行组间比较。结果:肉桂组和安慰剂组在最终AlC (8.8 vs. 8.7,P = 0.88)、AlC变化(0.3 vs. 0.0, P = 0.13)、每日胰岛素总摄入量或低血糖发作次数方面无显著差异。结论:肉桂不能有效改善青少年1型糖尿病患者的血糖控制。
OBJECTIVE - The purpose of this study was to determine the effect of cinnamon on glycemic control in adolescents with type I diabetes.RESEARCH DESIGN AND METHODS - Using a prospective, double-blind, placebo-controlled design, 72 adolescent type I diabetic subjects were treated in an outpatient setting with cinnamon (1 g/day) or an equivalent-appearing placebo for 90 days. AlC, total daily insulin intake, and adverse events were recorded and compared between groups.RESULTS- There were no significant differences in final AlC (8.8 vs. 8.7,P = 0.88), change in AlC (0.3 vs. 0.0, P = 0.13), total daily insulin intake, or number of hypoglycemic episodes between the cinnamon and placebo arms.CONCLUSIONS - Cinnamon is not effective for improving glycemic control in adolescents With type 1 diabetes.