Rapid identification of bacteria with a disposable colorimetric sensing array.

Rapid identification of bacteria with a disposable colorimetric sensing array.
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DOI:
10.1021/ja201634d
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发表时间:
2011-05-18
影响因子:
15
通讯作者:
Wittrig, Aaron E.
Wittrig, Aaron E.
中科院分区:
化学1区
文献类型:
--
作者:
Carey, James R.;Suslick, Kenneth S.;Hulkower, Keren I.;Imlay, James A.;Imlay, Karin R. C.;Ingison, Crystal K.;Ponder, Jennifer B.;Sen, Avijit;Wittrig, Aaron E.

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Rapid identification of both species and even specific strains of human pathogenic bacteria grown on standard agar have been achieved from the volatiles they produce using a disposable colorimetric sensor array in a Petri dish imaged with an inexpensive scanner. All ten strains of bacteria tested, including E. faecalis and S. aureus and their antibiotic resistant forms, were identified with 98.8% accuracy within 10 h, a clinically important timeframe. Furthermore, the colorimetric sensor arrays also prove useful as a simple research tool for the study of bacterial metabolism and as an easy method for the optimization of bacterial production of fine chemicals or other fermentation processes.
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