Comparative morphology and structural classification of retroviruses.
Comparative morphology and structural classification of retroviruses.
复制标题
逆转录病毒的比较形态和结构分类。
DOI：
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发表时间：
1996
影响因子：
--
通讯作者：
D. Hockley
中科院分区：
文献类型：
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作者：
M. Nermut;D. Hockley
Retroviruses are characterised by two exceptional features: reverse transcription and a process of maturation outside the host cell which transforms the primary non-infectious product of assembly into a mature, infectious virus particle — the virion. Electron microscopy played an important role in morphological characterization of individual retrovirus groups and the results became a basis for classification of retroviruses. In addition, electron microscopy has become an indispensable companion in biological and molecular biological research. Several excellent reviews have been published recently which provide the reader with the necessary information on retrovirus morphology (Gelderblom 1991; Gelderblom et al. 1991; Coffin 1992). The aim of our contribution will be to present recent data in relation to morphogenesis and its mechanism. We shall concentrate on structural aspects of the assembly process, considering the three-dimensional structure of the gag-encoded polyprotein and the organization of the gag protein shell which determines the overall shape of the virus.
薄片电子显微镜的计算机模拟预测了人类免疫缺陷病毒的包膜相关二十面体衣壳。
DOI：
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发表时间：
1988
期刊：
Laboratory investigation; a journal of technical methods and pathology
影响因子：
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作者：
Marx,PA;Munn,RJ;Joy,KI
通讯作者：
Joy,KI