Information and Metabolism in Bacterial Chemotaxis
Information and Metabolism in Bacterial Chemotaxis
复制标题
DOI：
10.3390/e15010311
复制
发表时间：
2013-01-01
期刊：
影响因子：
2.7
通讯作者：
Auletta, Gennaro
中科院分区：
文献类型：
--
作者：
Auletta, Gennaro
理论生物学中最重要的问题之一是了解生物体如何部署控制机制以维持其稳态并确保其生存。一个关键的问题是生物如何处理环境信息，以确保与环境进行适当的交换，即使是最基本的生命形式（即细菌）。在本文中，我提出了一个信息理论的制定大肠杆菌如何应对环境信息在趋化性，更一般地说，信息和生物物理（代谢）动力学之间的关系的控制论模型。
One of the most important issues in theoretical biology is to understand how control mechanisms are deployed by organisms to maintain their homeostasis and ensure their survival. A crucial issue is how organisms deal with environmental information in a way that ensures appropriate exchanges with the environment-even in the most basic of life forms (namely, bacteria). In this paper, I present an information theoretic formulation of how Escherichia coli responds to environmental information during chemotaxis and, more generally, a cybernetic model of the relationship between information and biophysical (metabolic) dynamics.