Cutaneous squamous cell carcinoma is associated with Lynch syndrome: widening the spectrum of Lynch syndrome‐associated tumours
Cutaneous squamous cell carcinoma is associated with Lynch syndrome: widening the spectrum of Lynch syndrome‐associated tumours
复制标题
皮肤鳞状细胞癌与林奇综合征相关：扩大林奇综合征相关肿瘤的范围
DOI：
10.1111/bjd.20139
复制
发表时间：
2021
影响因子：
10.3
通讯作者：
M. E. van Leerdam
中科院分区：
文献类型：
--
作者：
B. Ykema;F. Adan;M. Crijns;F. Bleeker;E. Dekker;M. Bekkenk;P. Snaebjornsson;M. E. van Leerdam
尊敬的编辑先生，Lynch综合征(LS)是由错配修复(MMR)基因之一的胚系突变引起的。1皮脂腺肿瘤和角化棘皮瘤是与LS相关的皮肤肿瘤，也称为Muir-Torre综合征。对于皮肤鳞状细胞癌(SCC)，已被认为与LS有关。
Dear Editor, Lynch syndrome (LS) is caused by a germline mutation in one of the mismatch repair (MMR) genes. Individuals with LS have an increased risk of developing colorectal and many other tumours including skin tumours.1 Sebaceous neoplasms and keratoacanthomas are skin tumours associated with LS, also known as Muir-Torre syndrome. For cutaneous squamous cell carcinoma (SCC), an association with LS has been suggested.