Effectiveness of a brief behavioral treatment for inner-city illicit drug users with elevated depressive symptoms: The life enhancement treatment for substance use (LETS Act!)

Effectiveness of a brief behavioral treatment for inner-city illicit drug users with elevated depressive symptoms: The life enhancement treatment for substance use (LETS Act!)
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DOI:
10.4088/jcp.v69n0116
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发表时间:
2008-01-01
影响因子:
5.3
通讯作者:
Lejuez, C. W.
Lejuez, C. W.
中科院分区:
医学2区
文献类型:
--
作者:
Daughters, Stacey B.;Braun, Ashley R.;Lejuez, C. W.

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目的:抑郁症在非法药物使用者中非常普遍,这种共同发生与较差的治疗结果有关。然而,已经有有限的经验注意到开发和评估行为干预的抑郁症非法药物使用者。本研究的目的是测试将抑郁症的简短行为干预纳入标准住院药物滥用治疗的有效性。方法:44名有轻度至中度抑郁症状的成年非法药物使用者(Beck抑郁量表-II [BDI-II]评分>= 10)接受住院药物滥用治疗的患者被随机分配到任何一种治疗(TAU)单独或TAU加简短的抑郁症行为治疗(即,《物质使用生命增强治疗法》(LETS Act!在基线时评估患者的DSM-IV精神病诊断、抑郁症状(汉密尔顿抑郁量表,BDI-II)、焦虑症状(贝克焦虑量表)和活动的享受和奖励价值(环境奖励观察量表)。在治疗后和2周随访时再次对患者进行评估。治疗满意度和损耗率也在治疗后进行了评估。资料收集自2005年11月至2006年3月。干预组(N = 22)在治疗后的抑郁、焦虑症状、活动的享受和奖励价值以及2周随访时的抑郁症状方面的改善明显大于TAU组(N = 22)。LETS法案!组也报告了显着更高的治疗满意度rates.Conclusions:这项研究支持LETS法案的疗效!在目前接受住院药物使用治疗的非法药物使用者中治疗抑郁症状和提高活动的享受和回报价值。数据还表明,干预可能有助于防止治疗流失。LETS法案!似乎是一个可行的和吝啬的干预措施,以改善抑郁症的治疗和住院药物滥用治疗环境中的整体护理质量。
Objective: Depression is highly prevalent among illicit drug users, and this co-occurrence is associated with poorer treatment outcomes. However, there has been limited empirical attention toward developing and assessing behavioral interventions for depression among illicit drug users. The objective of the current study was to test the efficacy of integrating a brief behavioral intervention for depression into standard inpatient substance abuse treatment.Method: Forty-four adult illicit drug users with mild to moderate depressive symptoms (Beck Depression Inventory-II [BDI-II] score >= 10) who were receiving inpatient substance abuse treatment were randomly assigned to either treatment as usual (TAU) alone or TAU plus brief behavioral therapy for depression (i.e., Life Enhancement Treatment for Substance Use [LETS Act!]). Patients were assessed at baseline for DSM-IV psychiatric diagnoses, depressive symptoms (Hamilton Rating Scale for Depression, BDI-II), anxiety symptoms (Beck Anxiety Inventory), and enjoyment and reward value of activities (Environmental Reward Observation Scale). Patients were again assessed at posttreatment and at 2-week follow-up. Treatment satisfaction and attrition rates also were assessed at posttreatment. Data were collected from November 2005 to March 2006.Results: Patients who received the LETS Act! intervention (N = 22) evidenced significantly greater improvements than the TAU group (N = 22) in severity of depression, anxiety symptoms, and enjoyment and reward value of activities at posttreatment and in depressive symptoms at 2-week follow-up. The LETS Act! group also reported significantly higher treatment satisfaction ratings.Conclusions: This study supports the efficacy of LETS Act! in treating depressive symptoms and improving the enjoyment and reward value of activities among illicit drug users currently receiving inpatient substance use treatment. Data also indicate the intervention may help prevent treatment attrition. LETS Act! appears to be a feasible and parsimonious intervention to improve the treatment of depression and overall quality of care within inpatient substance abuse treatment settings.