A latent class analysis of the past-30-day substance use patterns among lifetime cocaine users: Findings from a community sample in North Central Florida.
A latent class analysis of the past-30-day substance use patterns among lifetime cocaine users: Findings from a community sample in North Central Florida.
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DOI：
10.1016/j.abrep.2019.100170
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发表时间：
2019-06-01
影响因子：
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通讯作者：
Cottler, Linda B
中科院分区：
文献类型：
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作者：
Liu, Yiyang;Elliott, Amy L;Cottler, Linda B
目的：可卡因的使用日益增多，许多可卡因吸毒者使用多种物质。在多物质使用中，各种物质的使用之间的关系必然是复杂的。为了解决这一复杂性，我们使用潜在类别分析(LCA)来确定终生可卡因使用者中多种物质的使用模式，并检查这些模式、人口统计学和风险特征之间的关联。方法：正在进行的社区参与计划HealthStreet的成员被问及一生中和过去30天内使用可卡因、酒精、烟草、大麻和处方药、精神健康状况、最近急诊科(ED)就诊和人口统计学情况。LCA被用来在支持终生可卡因使用的个人中识别过去30天多物质使用的类别。结果：在1797名终生吸食可卡因的人中，确定了一个五类LCA模型：1)过去30天仅吸烟(45%)，2)过去30天酒精、大麻和烟草使用(31%)，3)过去30天烟草、处方阿片类药物和镇静剂使用(13%)，4)过去30天可卡因、酒精、大麻和烟草使用(9%)，5)过去30天可卡因和多种多物质使用(2%)。人口学、急诊科就诊和心理健康状况与班级成员身份有关。结论：约11%的终生可卡因吸毒者在过去30 天内使用可卡因，并有两种不同的同时使用药物模式。与目前的可卡因使用相比，处方药(阿片类药物和镇静剂)和复杂的多物质使用模式是负面结果的更强指标。可卡因与其他兴奋剂一起使用的频率不高。除了多种物质的使用，处方药的使用应该针对终生吸食可卡因的人进行干预。
OBJECTIVES: Cocaine use is increasing and many cocaine users engage in polysubstance use. Within polysubstance use, relationships among use of individual substances are necessarily complex. To address this complexity, we used latent class analysis (LCA) to identify patterns of polysubstance use among lifetime cocaine users and examine associations among these patterns, demographics, and risk profiles.METHODS: Members of HealthStreet, an ongoing community engagement program, were asked about lifetime and past 30-day use of cocaine, alcohol, tobacco, marijuana, and prescription medications, mental health conditions, recent Emergency Department (ED) visits and demographics. LCA was used to identify classes of past 30-day polysubstance use among individuals who endorsed lifetime cocaine use. Multinomial logistic regression identified factors associated with these classes.RESULTS: Among 1797 lifetime cocaine users, a five-class LCA model was identified: 1) past 30-day tobacco use only (45%), 2) past 30-day alcohol, marijuana and tobacco use (31%), 3) past 30-day tobacco, prescription opioid and sedative use (13%), 4) past 30-day cocaine, alcohol, marijuana and tobacco use (9%), 5) past 30-day cocaine and multiple polysubstance use (2%). Demographics, ED visits and mental health conditions were associated with class membership.CONCLUSIONS: Approximately 11% of lifetime cocaine users used cocaine in the past 30 days with two different concurrent substance use patterns. Prescription medication (opioids and sedatives) and complex polysubstance use patterns were stronger indicators of negative outcomes than current cocaine use. Cocaine was not used frequently with other stimulants. In addition to polysubstance use, prescription medication use should be targeted for intervention among lifetime cocaine users.