Extracellular vesicles, tissue factor, cancer and thrombosis - discussion themes of the ISEV 2014 Educational Day.
Extracellular vesicles, tissue factor, cancer and thrombosis - discussion themes of the ISEV 2014 Educational Day.
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DOI：
10.3402/jev.v4.26901
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发表时间：
2015
影响因子：
16
通讯作者：
Nieuwland R
中科院分区：
文献类型：
--
作者：
Gardiner C;Harrison P;Belting M;Böing A;Campello E;Carter BS;Collier ME;Coumans F;Ettelaie C;van Es N;Hochberg FH;Mackman N;Rennert RC;Thaler J;Rak J;Nieuwland R
虽然癌症和静脉血栓栓塞（VTE）之间的联系早已为人所知，但其机制仍知之甚少。循环组织因子承载细胞外囊泡已被提出作为在某些类型的癌症中观察到的VTE风险增加的可能解释。国际细胞外囊泡学会（ISEV）和国际血栓与止血学会（ISTH）于2014年4月联合举办了教育日活动，讨论该领域的最新进展。本次审查讨论了该事件的主题和随后的ISEV 2014会议。
Although the association between cancer and venous thromboembolism (VTE) has long been known, the mechanisms are poorly understood. Circulating tissue factor–bearing extracellular vesicles have been proposed as a possible explanation for the increased risk of VTE observed in some types of cancer. The International Society for Extracellular Vesicles (ISEV) and International Society on Thrombosis and Haemostasis (ISTH) held a joint Educational Day in April 2014 to discuss the latest developments in this field. This review discusses the themes of that event and the ISEV 2014 meeting that followed.