THE INFLUENCE OF THE HOST ON EXPRESSION OF INTESTINAL MICROBIAL ENZYME-ACTIVITIES INVOLVED IN METABOLISM OF FOREIGN COMPOUNDS
THE INFLUENCE OF THE HOST ON EXPRESSION OF INTESTINAL MICROBIAL ENZYME-ACTIVITIES INVOLVED IN METABOLISM OF FOREIGN COMPOUNDS
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DOI：
10.1111/j.1365-2672.1985.tb03359.x
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发表时间：
1985-12-01
期刊：
影响因子：
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通讯作者：
ROWLAND, IR
中科院分区：
文献类型：
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作者：
COLE, CB;FULLER, R;ROWLAND, IR
四种酶（β-葡糖苷酶，β-葡萄糖醛酸酶，硝酸还原酶和硝基还原酶）在选择的肠细菌（大肠杆菌，梭菌属，链球菌属，拟杆菌属和唾液乳杆菌）在体外和体内生长后进行测量。这五种菌株的活性不同，梭菌属对β-葡聚糖酶活性最高。葡糖苷酶，β-葡萄糖醛酸酶和硝基还原酶，以及E.大肠杆菌是硝酸还原酶最活跃的生产者。体外酶活性往往高于体外酶活性，但在某些情况下，比较活性相反。
The activities of four enzymes (.beta.-glucosidase, .beta.-glucuronidase, nitrate reductase and nitroreductase) in selected intestinal bacteria (Escherichia coli, Clostridium sp., Streptococcus sp., Bacteroides sp. and Lactobacillus salivarius) were measured after growth in vitro and in vivo. The five strains differed in their activities with Clostridium sp. being the most active for .beta.-glucosidase, .beta.-glucuronidase and nitroreductase, and E. coli the most active producer of nitrate reductase. Enzyme activity in vitro tended to be higher than in vitro but there were instances where the comparative activities were reversed.