STUDY OF AN EPIDEMIC OF NON-A, NON-B HEPATITIS - POSSIBILITY OF ANOTHER HUMAN HEPATITIS-VIRUS DISTINCT FROM POST-TRANSFUSION NON-A, NON-B TYPE
STUDY OF AN EPIDEMIC OF NON-A, NON-B HEPATITIS - POSSIBILITY OF ANOTHER HUMAN HEPATITIS-VIRUS DISTINCT FROM POST-TRANSFUSION NON-A, NON-B TYPE
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DOI：
10.1016/0002-9343(80)90200-4
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发表时间：
1980-01-01
影响因子：
5.9
通讯作者：
KHUROO, MS
中科院分区：
文献类型：
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作者：
KHUROO, MS
从1978年11月至1979年4月的6个月期间，在克什米尔山谷[印度]研究了一种常见的水源性病毒性肝炎流行。对乙型肝炎和甲型肝炎的高度敏感的血清学试验未能显示任何一种是肝炎的病因。在这6个月内接受4次筛查的该地区16,620名居民中，1.65%的人患病毒性肝炎。与病毒性肝炎患者有过接触的128人中，27.3%具有无黄疸型肝炎的生化特征。所研究患者的传播方式、潜伏期、临床特征和生化检测结果与甲型肝炎相似，与输血后的非甲、非乙型肝炎与乙型肝炎相似。确定了其粪口传播途径。
A common source waterborne epidemic of viral hepatitis was studied in Kashmir valley [India] over the 6 mo. period from Nov. 1978-April 1979. Highly sensitive serologic tests for hepatitis B and hepatitis A failed to reveal either one as an etiologic agent of hepatitis. Of 16,620 inhabitants of the area screened 4 times in these 6 mo., viral hepatitis developed in 1.65%. Of 128 persons who had contacts with patients who had viral hepatitis, 27.3% had biochemical features of anicteric hepatitis. The mode of spread of the epidemic, length of incubation, clinical features and biochemical test results of the patients studied resembled that of hepatitis A. These findings were in contrast to that of non-A, non-B hepatitis following transfusion, which closely resembles hepatitis B. Another human hepatitis virus may exist. The fecal oral route of its spread was established.