Development of a pixelated GSO gamma camera system with tungsten parallel hole collimator for single photon imaging.
Development of a pixelated GSO gamma camera system with tungsten parallel hole collimator for single photon imaging.
复制标题
开发带有钨平行孔准直器的像素化 GSO 伽马相机系统，用于单光子成像。
DOI：
10.1118/1.3673774
复制
发表时间：
2012
期刊：
影响因子：
3.8
通讯作者：
J. Hatazawa
中科院分区：
文献类型：
--
作者：
S. Yamamoto;H. Watabe;Y. Kanai;E. Shimosegawa;J. Hatazawa
目的
在使用单光子发射放射性核素的小动物成像中，需要高分辨率伽马相机。近年来，具有高量子效率的位置灵敏光电倍增管（PSPMT）得到了发展。通过将这些与具有相对低的光输出的非吸湿性衰减器相结合，高分辨率伽马相机可以变得对低能量伽马光子有用。因此，作者通过将像素化Ce掺杂Gd（2）SiO（5）（GSO）块与高量子效率PSPMT相结合来开发伽马相机。
方法
选择GSO作为闪烁体，因为其不吸湿且不含任何天然放射性。制作了1.9mm × 1.9mm × 7 mm的GSO晶体单元阵列。这些GSO与0.1 mm厚的反射器组合形成22 × 22矩阵，并与高量子效率PSPMT（H8500 C-100 MOD 8）光耦合。GSO伽马相机被封装在钨伽马射线屏蔽与钨像素化平行孔准直器，并测量的基本性能为钴-57伽马光子（122千电子伏）。
结果
在二维位置直方图中，所有像素都被清楚地分辨。能量分辨率为± 15%FWHM。使用20 mm厚的钨像素准直器，距离准直器表面40 mm处的空间分辨率为4.4 mm FWHM，灵敏度为1.05%。使用我们开发的伽马相机成功地获得了体模和小动物图像。
结论
这些结果证实了所开发的像素化GSO伽马相机具有作为低能伽马光子成像的有效仪器的潜力。
PURPOSE
In small animal imaging using a single photon emitting radionuclide, a high resolution gamma camera is required. Recently, position sensitive photomultiplier tubes (PSPMTs) with high quantum efficiency have been developed. By combining these with nonhygroscopic scintillators with a relatively low light output, a high resolution gamma camera can become useful for low energy gamma photons. Therefore, the authors developed a gamma camera by combining a pixelated Ce-doped Gd(2)SiO(5) (GSO) block with a high quantum efficiency PSPMT.
METHODS
GSO was selected for the scintillator, because it is not hygroscopic and does not contain any natural radioactivity. An array of 1.9 mm × 1.9 mm × 7 mm individual GSO crystal elements was constructed. These GSOs were combined with a 0.1-mm thick reflector to form a 22 × 22 matrix and optically coupled to a high quantum efficiency PSPMT (H8500C-100 MOD8). The GSO gamma camera was encased in a tungsten gamma-ray shield with tungsten pixelated parallel hole collimator, and the basic performance was measured for Co-57 gamma photons (122 keV).
RESULTS
In a two-dimensional position histogram, all pixels were clearly resolved. The energy resolution was ∼15% FWHM. With the 20-mm thick tungsten pixelated collimator, the spatial resolution was 4.4-mm FWHM 40 mm from the collimator surface, and the sensitivity was ∼0.05%. Phantom and small animal images were successfully obtained with our developed gamma camera.
CONCLUSIONS
These results confirmed that the developed pixelated GSO gamma camera has potential as an effective instrument for low energy gamma photon imaging.
GSO正电子/单光子成像探测器的研制
DOI：
--
发表时间：
2006
期刊：
Physics in Medicine and Biology Vol.51
影响因子：
--
作者：
S.Yamamoto;K.Matsumoto;M.Senda
通讯作者：
M.Senda
陶瓷Pr:LuAG闪烁体的基本性能
DOI：
--
发表时间：
2009
期刊：
IEEE Trans.Nucl.Sci 56
影响因子：
--
作者：
T.Yanagida;A.Yoshikawa;A.Ikesue;K.Kamada;Y.Yokota
通讯作者：
Y.Yokota