The assessment of breathlessness in pulmonary arterial hypertension: Reliability and validity of the Dyspnoea-12
The assessment of breathlessness in pulmonary arterial hypertension: Reliability and validity of the Dyspnoea-12
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DOI：
10.1177/1474515113514891
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发表时间：
2014-12-01
影响因子：
2.9
通讯作者：
Armstrong, Iain
中科院分区：
文献类型：
--
作者：
Yorke, Janelle;Armstrong, Iain
呼吸困难是肺动脉高压（PAH）的主要症状，但以前没有呼吸困难仪器已被测试的可靠性和有效性，这一人群。采用横断面设计，我们测试了呼吸困难-12（D-12）的心理测量学特性，用于评估PAH患者的呼吸困难。Pearson相关分析与世界卫生组织心功能分级（WHO FC）、明尼苏达心力衰竭-肺动脉高压生活量表（MLHF-PH）、医院焦虑抑郁量表（HADS）和6分钟步行距离试验（6 MWD）进行相关分析。参与者（n = 176）大多为女性（70.5%），平均年龄54.3 ± 14岁;诊断为特发性PAH（48.9%）、先天性心脏病（27.8%）和结缔组织病（23.3%）;大多数为WHO FC II（32.4%）和III（52.3%）。D-12表现出良好的内部一致性的总得分和两个组成部分的身体和情绪（克朗巴赫的0.95，0.93和0.94，分别）。D-12总分与MLHF-PH（r = 0.70）、HADS（焦虑r = 0.54和抑郁r = 0.68）、WHO FC（r = 0.49）和6 MWD（r = -0.26）显著相关。在PAH患者中，D-12 -一种简短的患者报告的呼吸困难严重程度测量方法，利用了身体和情绪成分，是一种可靠有效的工具。
Breathlessness is a cardinal symptom of pulmonary arterial hypertension (PAH); yet no breathlessness instrument has been previously tested for reliability and validity for this population. Using a cross-sectional design, we tested the psychometric properties of the Dyspnoea-12 (D-12), for the assessment of breathlessness in PAH. Pearson's correlations with World Health Organization functional class (WHO FC), Minnesota Living with Heart failure - pulmonary hypertension modified version (MLHF-PH), Hospital Anxiety and Depression scale (HADS) and 6-minute walk distance test (6MWD) were conducted. Participants (n = 176) were mostly female (70.5%), mean age 54.3 +/- 14 years; diagnosed with idiopathic PAH (48.9%), congenital heart disease (27.8%) and connective tissue disease (23.3%); and most were WHO FC II (32.4%) and III (52.3%). The D-12 showed excellent internal consistency for the total and two-component scores for physical and emotional (Cronbach's 0.95, 0.93 and 0.94, respectively). D-12 total score was significantly associated with MLHF-PH (r = 0.70), HADS (anxiety r = 0.54 and depression r = 0.68), WHO FC (r = 0.49), and 6MWD (r = -0.26). In patients with PAH, the D-12 - a short patient reported measure of breathlessness severity that taps the physical and emotional components, is a reliable and valid instrument.