Exhaled breath volatile alterations in pregnancy assessed with electronic nose

Exhaled breath volatile alterations in pregnancy assessed with electronic nose
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DOI:
10.3109/1354750x.2011.598562
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发表时间:
2011-09-01
期刊:
影响因子:
2.6
通讯作者:
Horvath, Ildiko
Horvath, Ildiko
中科院分区:
医学4区
文献类型:
--
作者:
Bikov, Andras;Pako, Judit;Horvath, Ildiko

文献摘要

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妊娠相关的加速代谢和氧化应激可能改变呼出的挥发性化合物模式(“呼吸纹”)。电子鼻可以区分“呼吸纹”与不同disorders.Objective:这是第一个研究评估的“呼吸纹”在怀孕during pregnancy.Material and methods:130名妇女参加了我们的研究(78怀孕与52非怀孕)。呼吸样本进行处理的电子鼻和分析,使用主成分analysis.Results:孕妇和非孕妇之间的呼出气模式的显着差异(p = 0.001)。结论:妊娠引起的呼出气的变化,需要考虑当孕妇呼吸系统疾病进行呼气测试。
Context: Pregnancy-linked accelerated metabolism and oxidative stress may alter the exhaled volatile compound pattern ("breathprint"). Electronic noses can distinguish "breathprints" associated with different disorders.Objective: This is the first study assessing alterations in "breathprint" during gestation.Material and methods: 130 women participated in our study (78 pregnant vs. 52 non-pregnant). Breath samples were processed by an electronic nose and analyzed using principal component analysis.Results: Significant differences were found in exhaled breath pattern between pregnant and non-pregnant women (p = 0.001).Conclusion: Pregnancy-induced changes in exhaled gases need to be considered when pregnant women with respiratory disorders carry out breath tests.