HIV transmission risk behavior among HIV-infected adults in Uganda: results of a nationally representative survey
HIV transmission risk behavior among HIV-infected adults in Uganda: results of a nationally representative survey
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DOI：
10.1097/qad.0b013e3282f56b53
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发表时间：
2008-03-12
期刊：
影响因子：
3.8
通讯作者：
Mermin, Jonathan
中科院分区：
文献类型：
--
作者：
Bunnell, Rebecca;Opio, Alex;Mermin, Jonathan
目的：评估乌干达艾滋病毒感染成人中与艾滋病毒传播风险行为相关的因素。设计：横断面和全国代表性研究（2004-2005年乌干达艾滋病毒/艾滋病血清行为调查）对18525名成年人（15-59岁）进行艾滋病毒和2型单纯疱疹病毒（HSV-2）检测。方法：对数据进行加权，得出具有全国代表性的结果。艾滋病毒感染者的性危险行为定义为最后一次接触时无保护的性行为。通过多变量分析，我们确定了与性活跃、了解艾滋病毒状况以及使用避孕和避孕套相关的因素。结果：在1092名艾滋病毒感染者中，64%为女性（中位年龄为33岁），84%患有2型单纯疱疹病毒，13%报告有一个终生伴侣（男性1%，女性23%）。21%的成年人知道自己的艾滋病毒状况，9%的成年人知道自己伴侣的艾滋病毒状况。77%的人性生活活跃，其中27%的人报告在最后一次性行为中使用安全套。在最后一次无保护的性接触中，84%是与配偶，13%是与稳定的伴侣。在同居的人中，40%的人有一个hiv阴性的配偶。那些知道自己感染艾滋病毒的人在最后一次性接触中使用避孕套的可能性是其他人的三倍[调整优势比（AOR）， 3.0；95%置信区间（CI）为1.9-4.71，而那些知道其伴侣的艾滋病毒状况的人使用避孕套的可能性是后者的2.3倍（AOR, 2.3； 95%置信区间，1.2-4.3）。结论：乌干达少数感染艾滋病毒的成年人知道自己感染了艾滋病毒；近一半的人处于不感染艾滋病毒的关系中，很少有人使用避孕套。了解自己和伴侣的艾滋病毒状况与增加避孕套的使用有关。迫切需要采取干预措施，支持艾滋病毒感染者及其伴侣接受检测。(C) 2008年威科健康利平科特威廉姆斯和威尔金斯。
Objective: Evaluate factors associated with HIV transmission risk behavior among HIV-infected adults in Uganda.Design: Cross-sectional and nationally representative study (2004-2005 Uganda HIV/AIDS Sero-Behavioral Survey) tested 18525 adults (15-59 years old) for HIV and herpes simplex virus type 2 (HSV-2).Methods: Data were weighted to obtain nationally representative results. Sexual-risk behavior by HIV-infected individuals was defined as unprotected sex at last encounter. Using multivariate analysis, we identified factors associated with being sexually active, knowing HIV status, and using contraception and condoms.Results: Of 1092 HIV-infected respondents, 64% were female (median age was 33 years), 84% had HSV-2, and 13% reported one lifetime partner (1% of men and 23% of women). Twenty-one percent of adults knew their HIV status and 9% knew their partners'. Seventy-seven percent were sexually active, of whom 27% reported condom use at last sex. Of last unprotected sexual encounters, 84% were with spouses and 13% with steady partners. Of cohabitating persons, 40% had an HIV-negative spouse. Those who knew their HIV status were three times more likely to use a condom at last sex encounter [adjusted odds ratio (AOR), 3.0; 95% confidence intervals (CI), 1.9-4.71 and those who knew their partners' HIV status were 2.3 ti mes more likely to use condoms (AOR, 2.3; 95% Cl, 1.2-4.3).Conclusions: A minority of HIV-infected adults in Uganda knew they had HIV infection; nearly half were in an HIV-discordant relationship, and few used condoms. Knowledge of HIV status, both one's own and one's partner's, was associated with increased condom use. Interventions to support HIV-infected persons and their partners to be tested are urgently needed. (C) 2008 Wolters Kluwer Health Lippincott Williams & Wilkins.