Perceived Stress, Severity of Asthma, and Quality of Life in Young Adults with Asthma
Perceived Stress, Severity of Asthma, and Quality of Life in Young Adults with Asthma
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DOI：
10.2332/allergolint.o-07-531
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发表时间：
2009-03-01
影响因子：
6.8
通讯作者：
Eboshida, Akira
中科院分区：
文献类型：
--
作者：
Kimura, Tomoaki;Yokoyama, Akihito;Eboshida, Akira
背景：患有哮喘症状的人的生活质量低于没有哮喘症状的人。本研究的目的是阐明年轻哮喘患者的生活质量与哮喘严重程度、感知压力以及过敏性疾病合并症等其他因素之间的关系。 方法：研究参与者为来自日本 29 个医疗中心的 695 名哮喘患者，年龄为 20-44 岁。我们从研究结果的分析中排除了 116 名患有严重疾病并发症、咳嗽变异性哮喘或阿司匹林不耐受哮喘的患者。患者完成了8项简短健康调查（SF-8）、气道问卷20（AQ20）和日本版感知压力量表（JPSS），他们的医生还提供了临床信息，包括诊断、并发症、哮喘严重程度以及肺功能和免疫学检查结果。结果：一般生活质量（SF-8）和疾病特异性生活质量（AQ20）之间存在弱相关性。 AQ 20 与肺功能和免疫学检测结果几乎没有关联，仅与过敏性鼻炎和食物过敏等合并症有轻微关联。 AQ20 与感知压力 (JPSS) 呈中等相关，但与哮喘严重程度的相关性较弱。多重Logistic模型表明，女性和20-34岁年龄组的哮喘严重程度与AQ20之间没有关系。结论：与疾病特定生活质量相关的主要变量是感知压力，其次是哮喘严重程度。哮喘患者的压力管理可以改善他们的生活质量。
Background: People suffering from asthmatic symptoms have a lower quality of life than those without. The aim of this study is to clarify the association of quality of life with the severity of asthma, perceived stress, and other factors such as the comorbidity of allergic diseases among young adults with asthma.Methods: The study participants were 695 asthma patients, aged 20-44 years, from 29 medical centers in Japan. We excluded from the analysis of the result of the study 116 patients with complications of serious diseases, cough-variant asthma or aspirin-intolerant asthma. The patients completed the 8-Item Short-Form Health Survey (SF-8), the Airways Questionnaire 20 (AQ20), and the Japanese version of the Perceived Stress Scale (JPSS) and their doctors also provided clinical information including diagnosis, complications, severity of asthma, and results of pulmonary function and immunological tests.Results: There was a weak correlation between the generic quality of life (SF-8) and the disease-specific quality of life (AQ20). The AQ 20 revealed almost no association with the results of pulmonary function and immunological tests, and only a slight association with comorbidity of allergic rhinitis and food allergy. The AQ20 showed a moderate relation with perceived stress (JPSS) but a weak association with the severity of asthma. The multiple logistic models demonstrated that there was no relationship between the severity of asthma and the AQ20 in females, and in the age group of 20-34 years.Conclusions: A major variable related to the disease-specific quality of life was perceived stress, followed by the severity of asthma. Stress management of patients with asthma may improve their quality of life.