SIZE OF METALLIC AND POLYETHYLENE DEBRIS PARTICLES IN FAILED CEMENTED TOTAL HIP REPLACEMENTS
SIZE OF METALLIC AND POLYETHYLENE DEBRIS PARTICLES IN FAILED CEMENTED TOTAL HIP REPLACEMENTS
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DOI：
10.1302/0301-620x.74b3.1587882
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发表时间：
1992-05-01
影响因子：
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通讯作者：
BULLOUGH, PG
中科院分区：
文献类型：
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作者：
LEE, JM;SALVATI, EA;BULLOUGH, PG
关于不同金属制成的全髋关节假体失败率不同的报道促使我们测量了失败的骨水泥关节成形术周围金属和聚乙烯颗粒碎屑的大小。我们使用了一种从组织中提取金属碎片的隔离法，以及一种常规制备光学和电子显微镜的非隔离法。标本取自30例股骨假体，其中钛合金(10例)、钴铬合金(10例)、不锈钢(10例)，分离法金属颗粒平均大小为0.8~1.0mU/m×1.5~1.8mU/m。非隔离法的平均大小为0.3-0.4亩-m，比未隔离的-0.6-0.7亩-m小得多。对于每种工艺，三种金属的颗粒大小相似。聚乙烯颗粒的平均尺寸为2到4微米乘以8到13微米。从失败的钛合金植入物中取出的组织比从钴铬和不锈钢植入物中取出的组织更大。我们的结果表明，除了金属颗粒的大小之外，其他因素，如合金的成分，以及碎片的数量和产生的速度，可能在髋关节置换失败中更重要。
Reports of differing failure rates of total hip prostheses made of various metals prompted us to measure the size of metallic and polyethylene particulate debris around failed cemented arthroplasties. We used an isolation method, in which metallic debris was extracted from the tissues, and a non-isolation method of routine preparation for light and electron microscopy. Specimens were taken from 30 cases in which the femoral component was of titanium alloy (10), cobalt-chrome alloy (10), or stainless steel (10).The mean size of metallic particles with the isolation method was 0.8 to 1.0-mu-m by 1.5 to 1.8-mu-m. The non-isolation method gave a significantly smaller mean size of 0.3 to 0.4-mu-m by 0.6 to 0.7-mu-m. For each technique the particle sizes of the three metals were similar.The mean size of polyethylene particles was 2 to 4-mu-m by 8 to 13-mu-m. They were larger in tissue retrieved from failed titanium-alloy implants than from cobalt-chrome and stainless-steel implants.Our results suggest that factors other than the size of the metal particles, such as the constituents of the alloy, and the amount and speed of generation of debris, may be more important in the failure of hip replacements.