Endoscopic third ventriculostomy for hydrocephalus in osteopetrosis: a case report and review of the literature.
Endoscopic third ventriculostomy for hydrocephalus in osteopetrosis: a case report and review of the literature.
复制标题
内镜下第三脑室造口术治疗石骨症脑积水：病例报告和文献综述。
DOI：
10.1007/s00381-018-3719-8
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Kohmura E.
中科院分区：
文献类型：
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作者：
Akutsu N;Koyama J;Kawamura A;Nagashima T;Taniguchi M;Kohmura E.
引言文献中很少有与石骨症相关的脑积水报道。作为分流手术的并发症，有两份关于因骨石化症患者钻孔处骨过度生长导致分流故障的报告。我们在此报告一个成功地用内视镜第三脑室造口术（ETV）治疗的石骨症合并脑积水的病例。病例报告在5个月大时，一个男性患者出现发育迟缓。头部计算机断层扫描（CT）显示三脑室脑积水伴小脑扁桃体疝。在7个月大时，他接受了枕下减压术和枕骨大孔减压术。术后脑积水未改善，患者转至我院。在12个月大时，脑积水成功地用ETV治疗。术后期间平安无事。术后CT表现出改善脑室size.ConclusionsThe病因脑积水在骨硬化症是不完全清楚，但是，已经有几个报告，其中ETV是有效的。ETV应被视为治疗石骨症脑积水的首选治疗方法，因为它避免了石骨症患者可能发生的特征性分流并发症。
IntroductionThere are very few reports in the literature associating in hydrocephalus in osteopetrosis. As a complication of shunt procedure, there are two reports on shunt malfunction due to osseous overgrowth at the burr hole in patients with osteopetrosis. We herein report a case of osteopetrosis with hydrocephalus that was successfully treated with endoscopic third ventriculostomy (ETV).Case reportAt 5 months of age, a male patient presented with developmental delay. Head computed tomography (CT) demonstrated triventricular hydrocephalus with a cerebellar tonsillar herniation. At 7 months of age, he underwent suboccipital decompression with decompression of the foramen magnum. The hydrocephalus did not improve postoperatively, and the patient was transferred to our hospital. At 12 months of age, the hydrocephalus was successfully treated with ETV. The postoperative period was uneventful. Postoperative CT demonstrated an improvement in the ventricle size.ConclusionsThe etiology of hydrocephalus in osteopetrosis is not completely understood; however, there have been several reports in which ETV was effective. ETV should be considered the treatment of choice for hydrocephalus in osteopetrosis, as it avoids the characteristic shunt complications that can occur in patients with osteopetrosis.