In vitro inhibition of endometrial cancer growth by a neonatal rat testicular secretory product.

In vitro inhibition of endometrial cancer growth by a neonatal rat testicular secretory product.
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新生大鼠睾丸分泌产物对子宫内膜癌生长的体外抑制作用。

DOI:
10.1210/jcem-52-4-817
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发表时间:
1981
期刊:
The Journal of clinical endocrinology and metabolism
影响因子:
--
通讯作者:
M. L. Stone
M. L. Stone
中科院分区:
--
文献类型:
--
作者:
Z. Rosenwaks;H. Liu;H. Jones;L. Tseng;M. L. Stone

文献摘要

被引文献

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The ability of a neonatal testicular product to inhibit cancer cell line growth of Mullerian origin was tested in an "in vitro" system. Preliminary experiments indicated that increasing concentration of neonatal rat testicular homogenates showed increasing endometrial cancer (HEC-1) cell growth inhibition. Further investigation revealed that testes organ culture, similarly, inhibited HEC-1 cell growth. It is, therefore, concluded that neonatal rat testes elaborated a substance (or substances) which may be effective as an anti-tumor agent.