Micro-CT examinations of trabecular bone samples at different resolutions: 14, 7 and 2 micron level.
Micro-CT examinations of trabecular bone samples at different resolutions: 14, 7 and 2 micron level.
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DOI：
10.3233/thc-1998-65-611
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发表时间：
1998-12
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影响因子：
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通讯作者：
F. Peyrin;F. Peyrin;M. Salomé;M. Salomé;P. Cloetens;A. Laval-Jeantet;E. Ritman;P. Rüegsegger
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文献类型：
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作者：
F. Peyrin;F. Peyrin;M. Salomé;M. Salomé;P. Cloetens;A. Laval-Jeantet;E. Ritman;P. Rüegsegger
层析成像技术对小梁骨结构的研究很有吸引力。目前，使用传统的x射线源或同步加速器源都可以获得大范围空间分辨率的3D图像，分辨率可能小到几微米。由于在技术上可以在不同的尺度上检查小梁结构，问题是要知道在每个尺度上可能得到什么类型的信息。为此，在三种不同的微ct系统（立方体素分别为14、6.7和1.4微米）上，对不同年龄（33至90岁）的健康女性的10个椎骨样本进行了不同分辨率的成像。从不同图像中提取的形态参数对比结果与空间分辨率对结构参数影响的仿真结果一致。结论是，14微米体素尺寸给出了相当好的小梁结构参数化。此外，同步辐射2微米级图像还显示了小梁表面不规则和破裂以及重塑区等有趣的特征。
Tomographic techniques are attractive for the investigation of trabecular bone architecture. Using either conventional X-ray sources or synchrotron sources currently allows the acquisition of 3D images in a wide range of spatial resolution that may be as small as a few micrometers. Since it is technically possible to examine trabecular architecture at different scales, a question is to know what type of information it is possible to get at each scale. For this purpose, a series of ten vertebrae samples from healthy females of different ages (33 to 90) was imaged at various resolutions on three different micro-CT systems (cubic voxel size respectively 14, 6.7 and 1.4 microm). The comparison of morphometric parameters extracted from the different images is in agreement with simulation results on the influence of spatial resolution on structure parameters. The conclusion is that a 14 microm voxel size gives a reasonably good parameterisation of trabecular architecture. Besides the synchrotron radiation 2 microm level images reveal interesting features on the irregularities and rupture of trabecular surface, and on remodeling zones.