Association between Electronic Cigarette Use and Asthma among High School Students in South Korea
Association between Electronic Cigarette Use and Asthma among High School Students in South Korea
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DOI：
10.1371/journal.pone.0151022
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发表时间：
2016-03-04
期刊：
影响因子：
3.7
通讯作者：
Paik, Samuel Y.
中科院分区：
文献类型：
--
作者：
Cho, Jun Ho;Paik, Samuel Y.
尽管电子烟（EC）越来越受欢迎，但人们对电子烟使用相关的健康结果知之甚少。本研究的目的是调查EC使用和asthma.MethodsThe研究设计是一个横断面研究之间的关联。共有35，904名高中生被纳入最终研究人群。哮喘的存在是基于一个学生的自我报告的医生诊断哮喘在过去的12 months.ResultsPrevalence率哮喘在'目前的EC用户'（n = 2，513）、“前EC使用者”（n = 2，078）和“从未EC使用者”（n = 31，313）分别为3.9%（n = 98）、2.2%（n = 46）和1.7%（n = 530）。比较“目前使用EC”与“从未使用EC”的患者，哮喘的未校正OR为2.36（95%CI：1.89-2.94）。为了控制传统香烟（CC）吸烟的影响，在将受试者按CC吸烟的三个类别分层后，（从未服用过CC、曾服用过CC和目前服用CC），在“从未服用CC”类别中，“目前服用EC”的哮喘患者的未校正OR为3.41（95%CI：1.79-6.49），调整后OR为2.74（95%CI：1.30-5.78）。严重的哮喘是反映了由于哮喘症状而缺课的天数;目前EC用户有最高的调整OR为严重哮喘相比，“从来没有EC”users.ConclusionsWhen相比，在韩国的高中生的参考人群，EC用户有增加的关联与哮喘，更有可能有天缺课由于严重的哮喘症状。总之，结果表明，使用EC可能是哮喘的一个危险因素。结果可能是有用的，在开发一个潜在的健康危害的EC评估的科学依据。
ObjectivesLittle is known about health outcomes related to electronic cigarette (EC) use, despite its growing popularity. The aim of this study is to investigate the association between EC use and asthma.MethodsThe study design is a cross-sectional study. A total of 35,904 high school students were included as the final study population. The presence of asthma was based on a student's self-reported doctor diagnosis of asthma in the past 12 months.ResultsPrevalence rates of asthmatics in 'current EC users' (n = 2,513), 'former EC users' (n = 2,078), and 'never EC users' (n = 31,313), were 3.9% (n = 98), 2.2% (n = 46) and 1.7% (n = 530), respectively. Comparing 'current EC' users with 'never EC' users, the unadjusted OR for asthma was 2.36 (95% CI: 1.89-2.94). In order to control for the effect of conventional cigarette (CC) smoking, after stratifying the subjects by the three CC smoking categories (never CC, former CC, and current CC), within the 'never CC' category, the unadjusted OR for asthma for 'current EC' users was 3.41 (95% CI: 1.79-6.49), and the adjusted OR was 2.74 (95% CI: 1.30-5.78). Severe asthma was reflected by the number of days absent from school due to asthma symptoms; current EC users had the highest adjusted OR for severe asthma compared to 'never EC' users.ConclusionsWhen compared to a reference population of high school students in South Korea, EC users have an increased association with asthma and are more likely to have had days absent from school due to severe asthma symptoms. In conclusion, the results indicate that EC use may be a risk factor for asthma. The results may be useful in developing a scientific basis for the evaluation of a potential health hazard by EC.