AGE DEPENDENCE OF FLOW VELOCITIES IN BASAL CEREBRAL-ARTERIES
AGE DEPENDENCE OF FLOW VELOCITIES IN BASAL CEREBRAL-ARTERIES
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DOI：
10.1136/adc.63.6.606
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发表时间：
1988-06-01
影响因子：
5.2
通讯作者：
WAIS, U
中科院分区：
文献类型：
--
作者：
BODE, H;WAIS, U
应用经颅多普勒超声检测大脑基底动脉血流速度。对25名出生后20天内的健康新生儿进行了纵向研究，并对112名1天至18岁的健康儿童进行了横断面研究。新生儿出生后20天内血流速度呈线性增加，出生体重和胎龄越大，血流速度越快。在5至6岁时记录了最大值。之后，速度线性下降到70%的最大值在18岁。参考值来自考虑年龄和出生体重的数据。流速的增加可能反映了生命最初几年脑血流量的增加。我们的研究结果也支持婴儿期脑血管阻力降低的假设。随着经颅多普勒超声技术和引入的参考值，正常和异常的颅内血流速度，现在可以评估所有儿科年龄组的非侵入性方法。
Flow velocities in the basal cerebral arteries were studied by the transcranial Doppler sonography. A longitudinal study was undertaken on 25 healthy newborn babies during the first 20 days of life, and a cross sectional study was performed on 112 healthy children between 1 day and 18 years of age. A rapid linear increase of flow velocities was found within the first 20 days with higher velocities in neonates of higher birth weight and gestational age. Maximal values were recorded at the age of 5 to 6 years. After that the velocities decreased linearly to 70% of their maximum at the age of 18 years. Reference values were derived from the data considering age and birth weight. The increasing flow velocities probably reflect the increasing cerebral blood flow during the first years of life. Our results also support the hypothesis of a decrease in cerebrovascular resistance during infancy. With the technique of transcranial Doppler sonography and the introduced reference values normal and abnormal intracranial flow velocities can now be assessed by non-invasive methods in all paediatric age groups.